Adiposity is central to aging and several chronic diseases. Adiposity encompasses not just
the excess adipose tissue but also body fat redistribution, fat infiltration, hypertrophy of …

The skeletal muscle plays a critical role in regulating systemic blood glucose homeostasis.
Impaired skeletal muscle glucose homeostasis associated with type 2 diabetes mellitus …

Glucagon rapidly and profoundly stimulates hepatic glucose production (HGP), but for
reasons that are unclear, this effect normally wanes after a few hours, despite sustained …

Mammals are protected from changes in environmental temperature by altering energetic
processes that modify heat production. Insulin is the dominant stimulus of glucose uptake …

Abstract Aims/Hypothesis Obesity increases deposition of extracellular matrix (ECM)
components of cardiac tissue. Since obesity aggregates with insulin resistance and heart …

The association between Alzheimer's disease and metabolic disorders as significant risk
factors is widely acknowledged. However, the intricate molecular mechanism intertwining …

Simple Summary The rising population of people with obesity has presented an important
need for the study of how adipocytes (fat cells) behave and affect biological function …

Regardless of its anatomical site, adipose tissue shares a common energy-storage role but
exhibits distinctive properties. Exploring the cellular and molecular heterogeneity of white …

Increased deposition of extracellular matrix (ECM) components such as collagens and
hyaluronan contributes to the pathogenesis of obesity-associated insulin resistance in …

The prevalence of obesity is increasing exponentially across the globe. The lack of effective
treatment options for long-term weight loss has magnified the enormity of this problem …