Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system
The ability to artificially control transcription is essential both to the study of gene function
and to the construction of synthetic gene networks with desired properties. Cas9 is an RNA …
and to the construction of synthetic gene networks with desired properties. Cas9 is an RNA …
Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
49624232&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
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Annotation and classification of CRISPR-Cas systems
KS Makarova, EV Koonin - CRISPR: methods and protocols, 2015 - Springer
The clustered regularly interspaced short palindromic repeats (CRISPR)-Cas (CRISPR-
associated proteins) is a prokaryotic adaptive immune system that is represented in most …
associated proteins) is a prokaryotic adaptive immune system that is represented in most …
First Report of CRISPR/Cas9 Mediated DNA-Free Editing of 4CL and RVE7 Genes in Chickpea Protoplasts
The current genome editing system Clustered Regularly Interspaced Short Palindromic
Repeats Cas9 (CRISPR/Cas9) has already confirmed its proficiency, adaptability, and …
Repeats Cas9 (CRISPR/Cas9) has already confirmed its proficiency, adaptability, and …
A decade of discovery: CRISPR functions and applications
R Barrangou, P Horvath - Nature microbiology, 2017 - nature.com
This year marks the tenth anniversary of the identification of the biological function of
CRISPR–Cas as adaptive immune systems in bacteria. In just a decade, the characterization …
CRISPR–Cas as adaptive immune systems in bacteria. In just a decade, the characterization …
[PDF][PDF] CRISPR-Cas systems: prokaryotes upgrade to adaptive immunity
R Barrangou, LA Marraffini - Molecular cell, 2014 - cell.com
Clustered regularly interspaced short palindromic repeats (CRISPR), and associated
proteins (Cas) comprise the CRISPR-Cas system, which confers adaptive immunity against …
proteins (Cas) comprise the CRISPR-Cas system, which confers adaptive immunity against …
RNA-guided genetic silencing systems in bacteria and archaea
Clustered regularly interspaced short palindromic repeat (CRISPR) are essential
components of nucleic-acid-based adaptive immune systems that are widespread in …
components of nucleic-acid-based adaptive immune systems that are widespread in …
Cas9 specifies functional viral targets during CRISPR–Cas adaptation
Clustered regularly interspaced short palindromic repeat (CRISPR) loci and their associated
(Cas) proteins provide adaptive immunity against viral infection in prokaryotes. Upon …
(Cas) proteins provide adaptive immunity against viral infection in prokaryotes. Upon …
[PDF][PDF] Co-transcriptional DNA and RNA cleavage during type III CRISPR-Cas immunity
Immune systems must recognize and destroy different pathogens that threaten the host.
CRISPR-Cas immune systems protect prokaryotes from viral and plasmid infection utilizing …
CRISPR-Cas immune systems protect prokaryotes from viral and plasmid infection utilizing …
Repurposing CRISPR-Cas12b for mammalian genome engineering
F Teng, T Cui, G Feng, L Guo, K Xu, Q Gao, T Li, J Li… - Cell discovery, 2018 - nature.com
The prokaryotic CRISPR-Cas adaptive immune systems provide valuable resources to
develop genome editing tools, such as CRISPR-Cas9 and CRISPR-Cas12a/Cpf1. Recently …
develop genome editing tools, such as CRISPR-Cas9 and CRISPR-Cas12a/Cpf1. Recently …