Unfortunately, there is no endogenous marker for hepatic clearance that can be used as a
guide for drug dosing. In order to predict the kinetic behaviour of drugs in cirrhotic patients …

Patients with liver cirrhosis exhibit several features of gut dysfunction which may contribute
to the development of cirrhosis complications as well as have an impact on nutritional status …

OBJECTIVES: Spontaneous bacterial peritonitis (SBP) is a frequent complication of
cirrhosis. Bacterial contamination of ascites fluid leading to SBP is caused by bacterial …

The basic management is similar for all patients with upper gastrointestinal (UGI) bleeding
regardless of the cause or whether chronic liver disease is present or absent. All patients …

Objective. Gastrointestinal symptoms can lead to decreased food intake and thereby
increased morbidity. There is a general lack of data on the prevalence of gastrointestinal …

Acid suppressive therapy, in the form of proton pump inhibitor (PPI), is widely used in
cirrhotic patients, often in indications which are not clearly justified. PPI facilitates enteric …

In 153 consecutive patients with cirrhosis weassessed:(1) the prevalence of IgG to
Helicobacterpylori and compared it with that found in 1010 blooddonors resident in the …

Background and Aim The aim of this study was to assess the impact of proton pump inhibitor
(PPI) intake on the development of spontaneous bacterial peritonitis (SBP) or other …

Background The frequency of gastrointestinal ulcerations is higher in cirrhotic patients than
in the normal population. It has been shown that pioglitazone exhibits gastroprotective …

Thrombocytopenia is a frequent complication in patients with cirrhosis. As many as 84% of
patients with cirrhosis have thrombocytopenia, and it is an independent variable indicative of …