目的基于加权基因共表达网络分析(WGCNA) 筛选Ⅰ 期胃癌(SIGC) 的预后因子并探讨其分子
机制. 方法通过WGCNA 分析癌症基因组图谱(TCGA) 中SIGC 患者的临床数据, 筛选影响SIGC …

Lipids are present within the cell nucleus where they engage with factors involved in gene
regulation. Cholesterol associates with chromatin in vivo and stimulates nucleosome …

Multiple mechanisms influence transcriptional control, with mounting evidence proving that
gene expression is directly correlated to the accessibility of the DNA sequence to RNA …

Transcriptional control is crucial for normal cellular development and is regulated through a
host of mechanisms. Among other methods, cells control transcription across the genome …

BASP1 is a multifunctional protein which has been found to regulate transcription in several
different cell lines through acting as a co-factor for WT1 or ERα. BASP1 has been reported to …

The SRPK1 gene encodes a protein kinase that phosphorylates a class of splice factors
called serine/arginine-rich proteins (SR proteins) modifying their ability to regulate …

Breast cancer ranks first among women with cancer. A feature of this type of cancer is a
relatively high percentage of hereditary cases. In half of these cases, genetic mutations and …

Interakcije između bioloških makromolekula imaju ključnu ulogu u osnovnim procesima u
živim organizmima, posreduju u metaboličkim putevima, putevima prenosa signala …

This thesis attempts to examine the relationship between central government and local
government during the reigns of Charles II and James II. Chapter I considers, in turn, the four …