[HTML][HTML] Epigenetic responses and the developmental origins of health and disease
D Goyal, SW Limesand, R Goyal - Journal of Endocrinology, 2019 - joe.bioscientifica.com
Maternal and paternal factors influence offspring development and program its genome for
successful postnatal life. Based on the stressors during gestation, the pregnant female …
successful postnatal life. Based on the stressors during gestation, the pregnant female …
[HTML][HTML] The role of epigenetic change in autism spectrum disorders
Autism spectrum disorders (ASD) are a heterogeneous group of neurodevelopmental
disorders characterized by problems with social communication, social interaction, and …
disorders characterized by problems with social communication, social interaction, and …
[HTML][HTML] DNA methylation and methyl-CpG binding proteins: developmental requirements and function
O Bogdanović, GJC Veenstra - Chromosoma, 2009 - Springer
DNA methylation is a major epigenetic modification in the genomes of higher eukaryotes. In
vertebrates, DNA methylation occurs predominantly on the CpG dinucleotide, and …
vertebrates, DNA methylation occurs predominantly on the CpG dinucleotide, and …
Epigenetics and cardiovascular disease
JM Ordovás, CE Smith - Nature Reviews Cardiology, 2010 - nature.com
Despite advances in the prevention and management of cardiovascular disease (CVD), this
group of multifactorial disorders remains a leading cause of mortality worldwide. CVD is …
group of multifactorial disorders remains a leading cause of mortality worldwide. CVD is …
The telomerase reverse transcriptase regulates chromatin state and DNA damage responses
K Masutomi, R Possemato, JMY Wong… - Proceedings of the …, 2005 - National Acad Sciences
Constitutive expression of telomerase prevents senescence and crisis by maintaining
telomere homeostasis. However, recent evidence suggests that telomerase is dynamically …
telomere homeostasis. However, recent evidence suggests that telomerase is dynamically …
[HTML][HTML] DNA methylation pattern in human zygotes and developing embryos
H Fulka, M Mrazek, O Tepla, J Fulka - Reproduction, 2004 - rep.bioscientifica.com
We report on observations of the global methylation/demethylation pattern of both pronuclei
in human zygotes and in early embryos up to the blastocyst stage. Our results demonstrate …
in human zygotes and in early embryos up to the blastocyst stage. Our results demonstrate …
[HTML][HTML] Conserved and divergent paths that regulate self-renewal in mouse and human embryonic stem cells
M Rao - Developmental biology, 2004 - Elsevier
The past few years have seen remarkable progress in our understanding of embryonic stem
cell (ES cell) biology. The necessity of examining human ES cells in culture, coupled with …
cell (ES cell) biology. The necessity of examining human ES cells in culture, coupled with …
Epigenetic control of gene expression in the lung
IV Yang, DA Schwartz - American journal of respiratory and critical …, 2011 - atsjournals.org
Epigenetics is traditionally defined as the study of heritable changes in gene expression
caused by mechanisms other than changes in the underlying DNA sequence. There are …
caused by mechanisms other than changes in the underlying DNA sequence. There are …
[HTML][HTML] Epigenetics and the germline
C Allegrucci, A Thurston, E Lucas, L Young - Reproduction, 2005 - rep.bioscientifica.com
Epigenetic processes affect three stages of germline development, namely (1) specification
and formation of primordial germ cells and their germline derivatives through lineage …
and formation of primordial germ cells and their germline derivatives through lineage …
Three epigenetic information channels and their different roles in evolution
There is increasing evidence for epigenetically mediated transgenerational inheritance
across taxa. However, the evolutionary implications of such alternative mechanisms of …
across taxa. However, the evolutionary implications of such alternative mechanisms of …