There is abundant evidence for abnormalities of the norepinephrine (NE) and serotonin
(5HT) neurotransmitter systems in depression and anxiety disorders. The majority of …

Tourette syndrome (TS) is a developmentally regulated neurobehavioral disorder
characterized by involuntary, stereotyped, repetitive movements. Recent anatomical and …

OBJECTIVE: Administration of placebo can result in a clinical response indistinguishable
from that seen with active antidepressant treatment. Functional brain correlates of this …

Definitive conclusions on the role of serotonin receptors and transporter in suicide and
depression have been elusive in studies of postmortem brain tissue. A number of …

Several neurochemical in vitro and in vivo imaging studies have been aimed at
characterizing the localization of serotonin receptors and transporters in the human brain. In …

Extracts of Hypericum perforatum (St. John's Wort) are widely used for the treatment of
depressive disorders and are unspecific inhibitors of the neuronal uptake of several …

Although the cardinal manifestations of Parkinson's disease (PD) are attributed to a decline
in dopamine levels in the striatum, a breadth of non-motor features and treatment-related …

The amygdala is a core component of neural circuits that mediate processing of emotional,
particularly anxiety and fear-related stimuli across species. In addition, the nuclear complex …

With recent studies using genetic, epigenetic, and other molecular and neurochemical
approaches, a new era has begun in understanding pathophysiology of suicide. Emerging …

INTRODUCTION: The primary approach in assessing the status of brain serotonin neurons
in human conditions such as major depression and exposure to the illicit drug ecstasy has …