Toxicity testing relies heavily on animals, especially rodents as part of the non-clinical
laboratory testing of substances. However, the use of mammalians and the number of …

The use of zebrafish (Danio rerio) has arisen as a promising biological platform for toxicity
testing of pesticides such as herbicides, insecticides, and fungicides. Therefore, it is relevant …

Considering the chemical complexity and toxicity data gaps of environmental mixtures, most
studies evaluate the chemical risk individually. However, humans are usually exposed to a …

Behavioural disruptions are sensitive indicators of alterations to normal animal physiology
and can be used for toxicity assessment. The small vertebrate zebrafish is a leading model …

Over the past twenty years, the prescription of antidepressant drugs has increased all over
the world. After their application, antidepressants, like other pharmaceuticals, are excreted …

During an oil spill, shallow, tropical coral reefs are likely to be simultaneously exposed to
high intensities of ultraviolet radiation (UVR), which can exacerbate the toxicity of petroleum …

Pharmaceuticals and personal care products (PPCPs) are released from multiple
anthropogenic sources and thus have a ubiquitous presence in the environment. The …

Whole effluent toxicity (WET) testing is commonly used to ensure that wastewater discharges
do not pose an unacceptable risk to receiving environments. Traditional WET testing …

Abstract The Capibaribe River provides water to a population of 1.7 million people in the
Brazilian northeast, while receiving agricultural runoff and industrial and domestic effluents …

The validation of high-throughput toxicity tests with invertebrate species is a key priority to
improve hazard assessment of new chemicals and increase the available test guidelines …