Bioavailability enhancement techniques for poorly aqueous soluble drugs and therapeutics
The low water solubility of pharmacoactive molecules limits their pharmacological potential,
but the solubility parameter cannot compromise, and so different approaches are employed …
but the solubility parameter cannot compromise, and so different approaches are employed …
Advances in oral drug delivery
The oral route is the most common route for drug administration. It is the most preferred
route, due to its advantages, such as non-invasiveness, patient compliance and …
route, due to its advantages, such as non-invasiveness, patient compliance and …
[HTML][HTML] Pharmaceutical amorphous solid dispersion: A review of manufacturing strategies
SV Bhujbal, B Mitra, U Jain, Y Gong, A Agrawal… - … Pharmaceutica Sinica B, 2021 - Elsevier
Amorphous solid dispersions (ASDs) are popular for enhancing the solubility and
bioavailability of poorly water-soluble drugs. Various approaches have been employed to …
bioavailability of poorly water-soluble drugs. Various approaches have been employed to …
Enhanced drug delivery by dissolution of amorphous drug encapsulated in a water unstable metal–organic framework (MOF)
K Suresh, AJ Matzger - Angewandte Chemie International …, 2019 - Wiley Online Library
Encapsulating a drug molecule into a water‐reactive metal–organic framework (MOF) leads
to amorphous drug confined within the nanoscale pores. Rapid release of drug occurs upon …
to amorphous drug confined within the nanoscale pores. Rapid release of drug occurs upon …
Mechanisms of increased bioavailability through amorphous solid dispersions: a review
A Schittny, J Huwyler, M Puchkov - Drug Delivery, 2020 - Taylor & Francis
Amorphous solid dispersions (ASDs) can increase the oral bioavailability of poorly soluble
drugs. However, their use in drug development is comparably rare due to a lack of basic …
drugs. However, their use in drug development is comparably rare due to a lack of basic …
The food matrix: implications in processing, nutrition and health
JM Aguilera - Critical reviews in food science and nutrition, 2019 - Taylor & Francis
The concept of food matrix has received much attention lately in reference to its effects on
food processing, nutrition and health. However, the term matrix is used vaguely by food and …
food processing, nutrition and health. However, the term matrix is used vaguely by food and …
Spray drying of pharmaceuticals and biopharmaceuticals: Critical parameters and experimental process optimization approaches
Spray drying is increasingly becoming recognized as an efficient drying and formulation
technique for pharmaceutical and biopharmaceutical processing. It offers significant …
technique for pharmaceutical and biopharmaceutical processing. It offers significant …
Coupling 3D printing with hot-melt extrusion to produce controlled-release tablets
The main objective of this work was to explore the potential of coupling fused deposition
modeling in three-dimensional (3D) printing with hot-melt extrusion (HME) technology to …
modeling in three-dimensional (3D) printing with hot-melt extrusion (HME) technology to …
Recent advances in amorphous solid dispersions: preformulation, formulation strategies, technological advancements and characterization
Amorphous solid dispersions (ASDs) are among the most popular and widely studied
solubility enhancement techniques. Since their inception in the early 1960s, the formulation …
solubility enhancement techniques. Since their inception in the early 1960s, the formulation …
Pharmapolymers in the 21st century: Synthetic polymers in drug delivery applications
The administration of drugs, as a main challenge of pharmaceutical and medicinal
applications, has certainly benefited from the application of synthetic polymers. However …
applications, has certainly benefited from the application of synthetic polymers. However …