Production of bioactive plant secondary metabolites through in vitro technologies—status and outlook

C Wawrosch, SB Zotchev - Applied Microbiology and Biotechnology, 2021 - Springer
Medicinal plants have been used by mankind since ancient times, and many bioactive plant
secondary metabolites are applied nowadays both directly as drugs, and as raw materials …

Hairy root cultures—a versatile tool with multiple applications

N Gutierrez-Valdes, ST Häkkinen… - Frontiers in plant …, 2020 - frontiersin.org
Hairy roots derived from the infection of a plant by Rhizobium rhizogenes (previously
referred to as Agrobacterium rhizogenes) bacteria, can be obtained from a wide variety of …

[HTML][HTML] Plant cell culture strategies for the production of natural products

M Ochoa-Villarreal, S Howat, SM Hong, MO Jang… - BMB …, 2016 - ncbi.nlm.nih.gov
Plants have evolved a vast chemical cornucopia to support their sessile lifestyles. Man has
exploited this natural resource since Neolithic times and currently plant-derived chemicals …

Nutritionally enhanced food crops; progress and perspectives

KL Hefferon - International journal of molecular sciences, 2015 - mdpi.com
Great progress has been made over the past decade with respect to the application of
biotechnology to generate nutritionally improved food crops. Biofortified staple crops such as …

Metabolic engineering in hairy roots: An outlook on production of plant secondary metabolites

D Bagal, AA Chowdhary, S Mehrotra, S Mishra… - Plant Physiology and …, 2023 - Elsevier
Plants are one of the vital sources of secondary metabolites. These secondary metabolites
have diverse roles in human welfare, including therapeutic implication. Nevertheless …

Application of hairy roots for phytoremediation: what makes them an interesting tool for this purpose?

E Agostini, MA Talano, PS González, ALW Oller… - Applied microbiology …, 2013 - Springer
In recent years, hairy roots (HRs) have been successfully used as research tools for
screening the potentialities of different plant species to tolerate, accumulate, and/or remove …

Both the mevalonate and the non-mevalonate pathways are involved in ginsenoside biosynthesis

S Zhao, L Wang, L Liu, Y Liang, Y Sun, J Wu - Plant cell reports, 2014 - Springer
Abstract Key Message When one of them was inhibited, the two pathways could
compensate with each other to guarantee normal growth. Moreover, the sterol biosynthesis …

Enhanced biosynthesis of bioactive abietane diterpenes by overexpressing AtDXS or AtDXR genes in Salvia sclarea hairy roots

M Vaccaro, N Malafronte, M Alfieri… - Plant Cell, Tissue and …, 2014 - Springer
Diterpenoids are important compounds for plant survival and have beneficial properties for
humans. Bioactive abietanic diterpenes are synthesized in roots of Salvia sclarea (eg …

Carrot hairy roots: factories for secondary metabolite production

MA Pedreño, L Almagro - Journal of experimental botany, 2020 - academic.oup.com
This article comments on: Barba-Espín G, Chen ST, Agnolet S, Hegelund JN, Stanstrup J,
Christensen JH, Müller R, Lütken H. 2020. Ethephon-induced changes in antioxidants and …

Rindera graeca (A. DC.) Boiss. & Heldr. (Boraginaceae) In Vitro Cultures Targeting Lithospermic Acid B and Rosmarinic Acid Production

K Sykłowska-Baranek, M Gaweł, Ł Kuźma, B Wileńska… - Molecules, 2023 - mdpi.com
The in vitro cultures of Rindera graeca, a rare endemic plant, were developed as a
sustainable source of phenolic acids. Various shoot and root cultures were established and …