[HTML][HTML] Incidence, risk factors, and clinical impact of major bleeding in hospitalized patients with COVID-19: a sub-analysis of the CLOT-COVID Study

J Nakamura, I Tsujino, S Yachi, M Takeyama… - Thrombosis journal, 2022 - Springer
Background The coronavirus disease 2019 (COVID-19) causes extensive coagulopathy and
a potential benefit of anticoagulation therapy has been documented for prevention of …

[HTML][HTML] Early effects of low molecular weight heparin therapy with soft-mist inhaler for COVID-19-induced hypoxemia: a phase IIb trial

M Erelel, M Kaskal, O Akbal-Dagistan, H Issever… - Pharmaceutics, 2021 - mdpi.com
In COVID-19-induced acute respiratory distress syndrome, the lungs are incapable of filling
with sufficient air, leading to hypoxemia that results in high mortality among hospitalized …

[HTML][HTML] To anticoagulate or not to anticoagulate in COVID-19: lessons after 2 years

JG Rizk, A Gupta, JG Lazo Jr, P Sardar… - … in Thrombosis and …, 2023 - thieme-connect.com
A hypercoagulable state associated with coronavirus disease 2019 (COVID-19) has been
well documented and is believed to be strongly supported by a proinflammatory state. The …

[HTML][HTML] Platelet count rose while D-dimer levels dropped as deaths and thrombosis declined—an observational study on anticoagulation shift in COVID-19

A Sjöström, JD Wersäll, A Warnqvist… - Thrombosis and …, 2021 - thieme-connect.com
Background High levels of D-dimer and low platelet counts are associated with poor
outcome in coronavirus disease 2019 (COVID-19). As anticoagulation appeared to improve …

CNN approach for predicting survival outcome of patients with COVID-19

A Chaddad, C Tanougast - IEEE Internet of Things Journal, 2023 - ieeexplore.ieee.org
Coronavirus disease 2019 (COVID-19) has been challenged specifically with the new
variant. The number of patients seeking treatment has increased significantly, putting …

[HTML][HTML] Factors associated with length of hospital stay among COVID-19 patients in Saudi Arabia: a retrospective study during the first pandemic wave

AK Alahmari, ZS Almalki, AA Albassam, MM Alsultan… - Healthcare, 2022 - mdpi.com
The COVID-19 pandemic severely affected healthcare systems and tested their
preparedness. To date, the length of hospital stay (LoHS) and its factors among COVID-19 …

[HTML][HTML] Targeting of Glycosaminoglycans in genetic and inflammatory Airway Disease

R Caird, M Williamson, A Yusuf, D Gogoi… - International Journal of …, 2022 - mdpi.com
In the lung, glycosaminoglycans (GAGs) are dispersed in the extracellular matrix (ECM)
occupying the interstitial space between the capillary endothelium and the alveolar …

[HTML][HTML] COVID-19 pandemic: A multidisciplinary perspective on the pathogenesis of a novel coronavirus from infection, immunity and pathological responses

J Yi, J Miao, Q Zuo, F Owusu, Q Dong, P Lin… - Frontiers in …, 2022 - frontiersin.org
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus2 (SARS-CoV-2), has spread to more than 200 countries and regions, having a …

Apixaban, an orally available anticoagulant, inhibits SARS-CoV-2 replication and its major protease in a non-competitive way

OA Chaves, CQ Sacramento… - Journal of Molecular …, 2022 - academic.oup.com
The severe coronavirus disease 2019 (COVID-19) is associated with coagulopathy.
Anticoagulants, such as low-molecular-weight heparin, warfarin, thrombin inhibitors, and …

[HTML][HTML] Diagnostic Accuracy of the RDW for Predicting Death in COVID-19

E Guaní-Guerra, B Torres-Murillo, C Muñoz-Corona… - Medicina, 2022 - mdpi.com
Background and Objectives: An association between high red blood cell distribution width
(RDW) and mortality has been found in several diseases, including infection and sepsis …