Defining responses to therapy and study outcomes in clinical trials of invasive fungal diseases: Mycoses Study Group and European Organization for Research and …

BH Segal, R Herbrecht, DA Stevens… - Clinical infectious …, 2008 - academic.oup.com
Invasive fungal diseases (IFDs) have become major causes of morbidity and mortality
among highly immunocompromised patients. Authoritative consensus criteria to diagnose …

Invasive pulmonary aspergillosis

MP Ledoux, B Guffroy, Y Nivoix… - … in respiratory and …, 2020 - thieme-connect.com
Invasive pulmonary aspergillosis (IPA) remains difficult to diagnose and to treat. Most
common risk factors are prolonged neutropenia, hematopoietic stem cell or solid organ …

Isavuconazole versus voriconazole for primary treatment of invasive mould disease caused by Aspergillus and other filamentous fungi (SECURE): a phase 3 …

JA Maertens, II Raad, KA Marr, TF Patterson… - The Lancet, 2016 - thelancet.com
Background Isavuconazole is a novel triazole with broad-spectrum antifungal activity. The
SECURE trial assessed efficacy and safety of isavuconazole versus voriconazole in patients …

Voriconazole resistance and mortality in invasive aspergillosis: a multicenter retrospective cohort study

PP Lestrade, RG Bentvelsen… - Clinical Infectious …, 2019 - academic.oup.com
Background Triazole resistance is an increasing problem in invasive aspergillosis (IA).
Small case series show mortality rates of 50%–100% in patients infected with a triazole …

Combination antifungal therapy for invasive aspergillosis: a randomized trial

KA Marr, HT Schlamm, R Herbrecht… - Annals of internal …, 2015 - acpjournals.org
This article has been corrected. The original version (PDF) is appended to this article as a
Supplement. Background: Invasive aspergillosis (IA) is associated with poor outcomes in …

Epidemiology and outcome of invasive fungal infection in adult hematopoietic stem cell transplant recipients: analysis of Multicenter Prospective Antifungal Therapy …

D Neofytos, D Horn, E Anaissie… - Clinical Infectious …, 2009 - academic.oup.com
Background. With use of data from the Prospective Antifungal Therapy (PATH) Alliance
registry, we performed this multicenter, prospective, observational study to assess the …

Factors associated with mortality in transplant patients with invasive aspergillosis

JW Baddley, DR Andes, KA Marr… - Clinical Infectious …, 2010 - academic.oup.com
Background. Invasive aspergillosis (IA) is an important cause of morbidity and mortality in
hematopoietic stem cell transplant (HSCT) and solid organ transplant (SOT) recipients. The …

[HTML][HTML] Invasive aspergillosis in patients with acute myeloid leukemia: a SEIFEM-2008 registry study

L Pagano, M Caira, A Candoni, M Offidani… - …, 2010 - ncbi.nlm.nih.gov
Invasive aspergillosis in patients with acute myeloid leukemia: a SEIFEM-2008 registry study -
PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI …

[HTML][HTML] Initial use of combination treatment does not impact survival of 106 patients with haematologic malignancies and mucormycosis: a propensity score analysis

A Kyvernitakis, HA Torres, Y Jiang, G Chamilos… - Clinical Microbiology …, 2016 - Elsevier
In view of the poor outcomes associated with mucormycosis in patients with haematologic
malignancies (HM) and haematopoietic cell transplant recipients, antifungal combinations …

Serum Galactomannan Versus a Combination of Galactomannan and Polymerase Chain Reaction–Based Aspergillus DNA Detection for Early Therapy of Invasive …

JM Aguado, L Vázquez… - Clinical Infectious …, 2015 - academic.oup.com
Background. The benefit of the combination of serum galactomannan (GM) assay and
polymerase chain reaction (PCR)–based detection of serum Aspergillus DNA for the early …