Apoptosis is a form of programmed cell death that results in the orderly and efficient removal
of damaged cells, such as those resulting from DNA damage or during development …

Apoptosis is the programmed cell death which maintains the healthy survival/death balance
in metazoan cells. Defect in apoptosis can cause cancer or autoimmunity, while enhanced …

Biomarkers of the meat quality are of prime importance for meat industry, which has to satisfy
consumers' expectations and, for them, meat tenderness is and will remain the primary and …

Apoptosis is a tightly regulated cell suicide program that plays an essential role in the
development and maintenance of tissue homeostasis by eliminating unnecessary or harmful …

Background Similarly to other tumor types, an imbalance between unrestrained cell
proliferation and impaired apoptosis appears to be a major unfavorable feature of …

Cancer is an uncontrolled growth of normal cells due to unchecked regulatory mechanisms
working inside the rapidly dividing cells. In this complex cancer disease treatment, various …

Cancer is a complex progressive multistep disorder that results from the accumulation of
genetic and epigenetic abnormalities, which lead to the transformation of normal cells into …

Survivin, the smallest member of IAP (inhibitor of apoptosis) family, is a dual functional
protein acting as a critical apoptosis inhibitor and key cell cycle regulator. Survivin is usually …

Searching for new strategies to bypass apoptosis resistance, we investigated the potential of
the Smac mimetic BV6 in Jurkat leukemia cells deficient in key molecules of the death …

Abstract The Inhibitor of Apoptosis proteins (IAPs) are a family of proteins that are mainly
known for their anti-apoptotic activity and ability to directly bind and inhibit caspases. Recent …