[HTML][HTML] Fatty acid synthesis in glial cells of the CNS

AV Garcia Corrales, M Haidar, JFJ Bogie… - International Journal of …, 2021 - mdpi.com
Fatty acids (FAs) are of crucial importance for brain homeostasis and neural function. Glia
cells support the high demand of FAs that the central nervous system (CNS) needs for its …

Mitochondrial Dysfunction and Alpha‐Lipoic Acid: Beneficial or Harmful in Alzheimer's Disease?

SM Dos Santos, CFR Romeiro… - Oxidative medicine …, 2019 - Wiley Online Library
Alzheimer's disease (AD) is a neurodegenerative disorder characterised by impairments in
the cognitive domains associated with orientation, recording, and memory. This pathology …

α‐Lipoic acid alleviates ferroptosis in the MPP+‐induced PC12 cells via activating the PI3K/Akt/Nrf2 pathway

L Liu, S Yang, H Wang - Cell Biology International, 2021 - Wiley Online Library
Parkinson's disease (PD) is a typical neurodegenerative disease. α‐Lipoic acid (α‐LA) can
reduce the incidence of neuropathy. The present study explored the role and mechanism of …

[HTML][HTML] Antioxidant and anti-inflammatory effects of α-lipoic acid on lipopolysaccharide-induced oxidative stress in rat kidney

B Skibska, E Kochan, A Stanczak, A Lipert… - Archivum Immunologiae …, 2023 - Springer
Abstract α-Lipoic acid (α-LA) is a naturally occurring organosulfur component. Oxidative
stress plays an essential role in the pathogenesis of various diseases, such as kidney and …

A fully transparent, flexible PEDOT: PSS–ITO–Ag–ITO based microelectrode array for ECoG recording

W Yang, Y Gong, CY Yao, M Shrestha, Y Jia, Z Qiu… - Lab on a Chip, 2021 - pubs.rsc.org
Integrative neural interfaces combining neurophysiology and optogenetics with neural
imaging provide numerous opportunities for neuroscientists to study the structure and …

Encapsulation and stabilization of α-lipoic acid in cyclodextrin inclusion complex electrospun nanofibers: Antioxidant and fast-dissolving α-lipoic acid/cyclodextrin …

A Celebioglu, T Uyar - Journal of agricultural and food chemistry, 2019 - ACS Publications
In this study, electrospinning of nanofibers from alpha-lipoic acid/cyclodextrin inclusion
complex systems was successfully performed without having any polymeric matrix. Alpha …

[HTML][HTML] Metal chelation therapy and Parkinson's disease: A critical review on the thermodynamics of complex formation between relevant metal ions and promising or …

M Tosato, V Di Marco - Biomolecules, 2019 - mdpi.com
The present review reports a list of approximately 800 compounds which have been used,
tested or proposed for Parkinson's disease (PD) therapy in the year range 2014–2019 …

[HTML][HTML] Recent developments in encapsulation of α-lipoic acid for enhanced bioavailability and stability

P Choudhary, S Dutta, JA Moses… - Quality Assurance and …, 2023 - qascf.com
α-lipoic acid (LA) is a potent antioxidant available in various plant and animal sources. Of
late, there is high market demand for LA-based nutraceuticals, owing to enhanced …

Role of lipoic acid in multiple sclerosis

H Xie, X Yang, Y Cao, X Long… - CNS neuroscience & …, 2022 - Wiley Online Library
Lipoic acid (LA) is an endogenous antioxidant that exists widely in nature. Supplementation
with LA is a promising approach to improve the outcomes of patients with multiple sclerosis …

Aspirin-loaded cross-linked lipoic acid nanodrug prevents postoperative tumor recurrence by residual cancer cell killing and inflammatory microenvironment …

P Jing, Y Luo, Y Chen, J Tan, C Liao… - Bioconjugate …, 2023 - ACS Publications
In addition to residual cancer cells, the surgery resection-induced hyperinflammatory
microenvironment is a key factor that leads to postsurgical cancer recurrence. Herein, we …