Objectives Systemic sclerosis (SSc) is a complex disease of unknown aetiology in which
inflammation and fibrosis lead to multiple organ damage. There is currently no effective …

Background Mesenchymal stem cell (MSC)-based cartilage tissue regeneration is a
treatment with great potential. How to enhance the MSC chondrogenic differentiation is a …

The cellular complexity of the endochondral bone underlies its essential and pleiotropic
roles during organismal life. While the adult bone has received significant attention, we still …

Osteoporosis and obesity are two severe complex diseases threatening public health
worldwide. Both diseases are under strong genetic determinants as well as genetically …

The overall objective of this study was to investigate the mechanism of inflammation on
chondrocyte injury and the protective effect of catalpol on chondrocytes in an inflammatory …