Long non‐coding RNAs as potential biomarkers in the prognosis and diagnosis of lung cancer: A review and target analysis

Y Aftabi, K Ansarin, D Shanehbandi, M Khalili… - IUBMB …, 2021 - Wiley Online Library
Long non‐coding RNAs (lncRNA) have been emerged as a novel class of molecular
regulators in cancer. They are dysregulated in many types of cancer; however, there is not …

LncRNA LINC00460: Function and mechanism in human cancer

X Chen, J Song, X Wang, D Sun, Y Liu… - Thoracic …, 2022 - Wiley Online Library
Abstract Long non‐coding RNAs (LncRNAs), which are more than 200 nucleotides in length
and with limited protein‐coding potential, play vital roles in the pathogenesis, tumorigenesis …

Construction of a nomogram based on a hypoxia-related lncRNA signature to improve the prediction of gastric cancer prognosis

Q Chen, L Hu, K Chen - Frontiers in Genetics, 2020 - frontiersin.org
Background Gastric cancer is one of the most common malignant tumors and has a poor
prognosis. Hypoxia is related to the poor prognosis of cancer patients. We searched for …

MicroRNAs as the critical regulators of tyrosine kinase inhibitors resistance in lung tumor cells

A Maharati, AS Zanguei, G Khalili-Tanha… - Cell Communication and …, 2022 - Springer
Lung cancer is the second most common and the leading cause of cancer related deaths
globally. Tyrosine Kinase Inhibitors (TKIs) are among the common therapeutic strategies in …

Emerging role of noncoding RNAs in EGFR TKI-resistant lung cancer

J Li, P Li, J Shao, S Liang, Y Wan, Q Zhang, C Li, Y Li… - Cancers, 2022 - mdpi.com
Simple Summary The introduction of epidermal growth factor receptor (EGFR)-tyrosine
kinase inhibitors (TKIs) has revolutionized the treatment of lung cancer. Nevertheless, TKI …

[HTML][HTML] The functional role of long non-coding RNAs and their underlying mechanisms in drug resistance of non-small cell lung cancer

H Zhou, B Feng, M Abudoureyimu, Y Lai, X Lin, C Tian… - Life sciences, 2020 - Elsevier
Background Non-small cell lung cancer (NSCLC) is the most commonly diagnosed solid
cancer and the main origin of cancer-related deaths worldwide. Current strategies to treat …

A review on the role of miR-149-5p in the carcinogenesis

S Ghafouri-Fard, T Khoshbakht, BM Hussen… - International journal of …, 2021 - mdpi.com
miR-149 is an miRNA with essential roles in carcinogenesis. This miRNA is encoded by the
MIR149 gene on 2q37. 3. The miR-149 hairpin produces miR-149-5p and miR-149-3p …

MiR-149-5p: an Important miRNA regulated by competing endogenous RNAs in diverse human cancers

F Ren, Y Yao, X Cai, Y Cai, Q Su, G Fang - Frontiers in Oncology, 2021 - frontiersin.org
MicroRNAs (miRNAs) consist of a large family of small, non-coding RNAs with the ability to
result in gene silencing post-transcriptionally. With recent advances in research technology …

Long non-coding RNAs and cancer mechanisms: Immune cells and inflammatory cytokines in the tumor microenvironment

P Yang, J Ding, Y Bian, Z Ma, K Wang, J Li - Medical Oncology, 2022 - Springer
Chronic inflammation and immune response are two central hallmarks of the tumor
microenvironment (TME), teeming with immune cells and inflammatory cytokines that …

Tumor-suppressive and oncogenic roles of microRNA-149-5p in human cancers

Y Shen, N Zhao, N Zhao, X Hu, X He, Y Xu… - International Journal of …, 2022 - mdpi.com
Malignant tumors are always a critical threat to human health, with complex pathogenesis,
numerous causative factors, and poor prognosis. The features of cancers, such as gene …