Understanding normal and cancer stem cells may provide insight into the origin of and new
therapeutics for prostate cancer. Normal and cancer stem cells in prostate have recently …

The concept of reversing chronic kidney disease (CKD) has been intensively researched
over the past decade. Indeed, as the prevalence of end-stage renal disease is constantly on …

Following kidney injury, repair can result in functional tissue becoming a patch of cells and
disorganized extracellular matrix—a scar—or it can recapitulate the original tissue …

Abstract Background Mesenchymal stromal cells (MSCs) and renal stem/progenitors
improve the recovery of acute kidney injury (AKI) mainly through the release of paracrine …

The cancer stem cell (CSC) model proposes that tumors have a hierarchical organization in
which only some cells indefinitely self-renew and thereby sustain tumor growth. In addition …

Recently, we have identified a population of renal progenitor cells in human kidneys
showing regenerative potential for injured renal tissue of SCID mice. We demonstrate here …

Acute kidney injury is followed by regeneration of damaged renal tubular epithelial cells.
The purpose of this study was to test the hypothesis that renal stem cells exist in the adult …

Terminally differentiated cells can be reprogrammed to pluripotency or directly to another
differentiated cell type in vitro, a capacity termed cellular plasticity. Plasticity is not limited to …

Stem cells play increasingly prominent roles in tissue engineering and regenerative
medicine. Pluripotent embryonic stem (ES) cells theoretically allow every cell type in the …

The term “cancer stem cell”(CSC) refers to a cancer cell with the following features:
clonogenic ability, the expression of stem cell markers, differentiation into cells of different …