BACKGROUND While oocyte IVM is practiced sporadically it has not achieved widespread
clinical practice globally. However, recently there have been some seminal advances in our …

In vitro maturation (IVM) of human immature oocytes has been shown to be a viable option
for patients at risk of ovarian hyperstimulation syndrome (OHSS), those seeking urgent …

STUDY QUESTION Does a chemically defined maturation medium supplemented with
FGF2, LIF, and IGF1 (FLI) improve in vitro maturation (IVM) of cumulus–oocyte complexes …

Background Development of ovarian follicles is regulated by a complex interaction of intra‐
and extra‐follicular signals. Oocyte‐derived paracrine factors (ODPFs) play a central role in …

Purpose This study evaluated the 24-month cumulative live birth rate (CLBR) for women with
polycystic ovary syndrome (PCOS) or high antral follicle count (AFC) who underwent oocyte …

In vitro maturation (IVM) is an alternative assisted reproductive technology with reduced
hormone-related side effects and treatment burden compared to conventional IVF …

生长分化因子-9 (growth differentiation factor-9, GDF-9) 和骨形态生成蛋白-15 (bone
morphogenetic protein-15, BMP-15) 是转化生长因子-3 (transforming growth factor-3, TGF-3) …

In vitro oocyte maturation (IVM) is an assisted reproductive technology (ART) alternative to
conventional IVF. IVM refers to in vitro maturation of immature cumulus-oocyte-complexes …

Infertility is becoming a more recurrent issue affecting 15% of couples on average as of
2022, with infertility being defined as the inability to conceive after 12 months of unprotected …

Abstract Background: Zishen Yutai Pill (ZYP), a traditional Chinese patent medicine, is often
used for the prevention of recurrent miscarriage and threatened abortion. However, ZYP's …