Could SARS-CoV-2 spike protein be responsible for long-COVID syndrome?

TC Theoharides - Molecular Neurobiology, 2022 - Springer
SARS-CoV-2 infects cells via its spike protein binding to its surface receptor on target cells
and results in acute symptoms involving especially the lungs known as COVID-19. However …

[HTML][HTML] Diversity in heat shock protein families: functional implications in virus infection with a comprehensive insight of their role in the HIV-1 life cycle

K Iyer, K Chand, A Mitra, J Trivedi, D Mitra - Cell Stress and Chaperones, 2021 - Elsevier
Heat shock proteins (HSPs) are a group of cellular proteins that are induced during stress
conditions such as heat stress, cold shock, UV irradiation and even pathogenic insult. They …

Cyanidin-3-O-glucoside and peonidin-3-O-glucoside-rich fraction of black rice germ and bran suppresses inflammatory responses from SARS-CoV-2 spike …

W Semmarath, S Mapoung, S Umsumarng, P Arjsri… - Nutrients, 2022 - mdpi.com
Black rice is a functional food that is high in anthocyanin content, primarily C3G and P3G. It
possesses nutraceutical properties that exhibit a range of beneficial effects on human …

[PDF][PDF] Be aware of SARS-CoV-2 spike protein: There is more than meets the eye

TC Theoharides, P Conti - J Biol Regul Homeost Agents, 2021 - mastcellmaster.com
The COVID-19 pandemic necessitated the rapid production of vaccines aimed at the
production of neutralizing antibodies against the COVID-19 spike protein required for the …

Incorporating the molecular mimicry of environmental antigens into the causality of autoimmune hepatitis

AJ Czaja - Digestive Diseases and Sciences, 2023 - Springer
Molecular mimicry between foreign and self-antigens has been implicated as a cause of
autoimmune hepatitis in experimental models and cross-reacting antibodies in patients. This …

Effects of cell proteostasis network on the survival of SARS-CoV-2

F Khomari, M Nabi-Afjadi, S Yarahmadi… - Biological Procedures …, 2021 - Springer
The proteostasis network includes all the factors that control the function of proteins in their
native state and minimize their non-functional or harmful reactions. The molecular …

Protein Quality Control Systems and ER Stress as Key Players in SARS-CoV-2-Induced Neurodegeneration

E Gavilán, R Medina-Guzman… - Cells, 2024 - mdpi.com
The COVID-19 pandemic has brought to the forefront the intricate relationship between
SARS-CoV-2 and its impact on neurological complications, including potential links to …

Essential considerations during vaccine design against COVID-19 and review of pioneering vaccine candidate platforms

M Bayat, Y Asemani, S Najafi - International Immunopharmacology, 2021 - Elsevier
The calamity of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV2),
COVID-19, is still a global human tragedy. To date, no specific antiviral drug or therapy has …

Transcriptional Profiling of SARS-CoV-2-Infected Calu-3 Cells Reveals Immune-Related Signaling Pathways

EPV Pereira, SM da Silva Felipe, RM de Freitas… - Pathogens, 2023 - mdpi.com
The COVID-19 disease, caused by the Severe Acute Respiratory Syndrome Coronavirus 2
(SARS-CoV-2), emerged in late 2019 and rapidly spread worldwide, becoming a pandemic …

The chaperone system in autoimmunity, inflammation, and virus-induced diseases: Role of chaperonins

AJL Macario, EC de Macario - Stress: Immunology and Inflammation, 2024 - Elsevier
Stress caused by diverse stressors, eg, virus infection, affects multiple cells and tissues and
demands action of antistress mechanisms, eg, the chaperone system (CS). Its chief …