Morphologic variants of pancreatic neuroendocrine tumors: clinicopathologic analysis and prognostic stratification

Y Xue, MD Reid, B Pehlivanoglu, RC Obeng… - Endocrine …, 2020 - Springer
Better prognostication/stratification of pancreatic neuroendocrine tumors (PanNETs) is
needed. In this detailed morpheomic study of 163 resected PanNETs, 11 unusual variants …

Role of endoscopic ultrasound in the diagnosis of pancreatic neuroendocrine neoplasms

T Ishii, A Katanuma, H Toyonaga, K Chikugo… - Diagnostics, 2021 - mdpi.com
Although pancreatic neuroendocrine neoplasms (PNENs) are relatively rare tumors, their
number is increasing with advances in diagnostic imaging modalities. Even small lesions …

[HTML][HTML] Surgery for metastatic pancreatic neuroendocrine tumors: a narrative review

JK Williams, JL Schwarz… - Hepatobiliary Surgery and …, 2023 - ncbi.nlm.nih.gov
Surgery for metastatic pancreatic neuroendocrine tumors: a narrative review - PMC Back to
Top Skip to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage …

The C-circle biomarker is secreted by alternative-lengthening-of-telomeres positive cancer cells inside exosomes and provides a blood-based diagnostic for ALT …

YY Chen, R Dagg, Y Zhang, JHY Lee, R Lu… - Cancers, 2021 - mdpi.com
Simple Summary A clinical test for alternative-lengthening-of-telomeres (ALT) could assist
with cancer diagnosis and monitoring of disease progression. ALT-targeted anticancer …

DAXX mutations as potential genomic markers of malignant evolution in small nonfunctioning pancreatic neuroendocrine tumors

M Cives, S Partelli, R Palmirotta, D Lovero… - Scientific reports, 2019 - nature.com
Management of localized well-differentiated pancreatic neuroendocrine tumors (panNETs)
is controversial and primarily dependent on tumor size. Upfront surgery is usually …

Pancreatic neuroendocrine neoplasms: updates on genomic changes in inherited tumour syndromes and sporadic tumours based on WHO classification

H Ishida, AK Lam - Critical Reviews in Oncology/Hematology, 2022 - Elsevier
Pancreatic neuroendocrine neoplasms (PanNENs) are the neuroendocrine neoplasms with
greatest rate of increase in incidence. Approximately 10% of PanNENs arise as inherited …

Genetic and epigenetic prognosticators of neuroendocrine tumours of the GI tract, liver, biliary tract and pancreas: A systematic review and meta‐analysis

C Mestre‐Alagarda, R Srirajaskanthan, Y Zen… - …, 2024 - Wiley Online Library
Multiple recurrent genetic and epigenetic aberrations have been associated with worse
prognosis in multiple studies of neuroendocrine tumours (NETs), but these have been …

Alternative lengthening of telomeres (ALT) in pancreatic neuroendocrine tumors: ready for prime-time in clinical practice?

C Luchini, RT Lawlor, S Bersani, C Vicentini… - Current Oncology …, 2021 - Springer
Abstract Purpose of Review Alternative lengthening of telomeres (ALT) is a telomerase-
independent mechanism used by some types of malignancies, including pancreatic …

Somatostatin receptor activity assessed by 68Ga-DOTATOC PET can preoperatively predict DAXX/ATRX loss of expression in well-differentiated pancreatic …

P Mapelli, C Bezzi, F Muffatti, S Ghezzo… - European Journal of …, 2023 - Springer
Purpose To evaluate the role of 68Ga-DOTATOC PET parameters in predicting DAXX/ATRX
loss of expression in patients with Pancreatic neuroendocrine tumors (PanNET) candidate to …

[HTML][HTML] Pancreatic neuroendocrine neoplasms: current state and ongoing controversies on terminology, classification and prognostication

OC Taskin, CN Clarke, M Erkan, S Tsai… - Journal of …, 2020 - ncbi.nlm.nih.gov
Significant improvements have taken place in our understanding of classification
neuroendocrine neoplasms of the pancreas in the past decade. These are now regarded in …