[HTML][HTML] Targeted next-generation sequencing of well-differentiated rectal, gastric, and appendiceal neuroendocrine tumors to identify potential targets

HY Park, MJ Kwon, HS Kang, YJ Kim, NY Kim, MJ Kim… - Human Pathology, 2019 - Elsevier
Rectal neuroendocrine tumors (NETs) are the most common gastrointestinal (GI) NETs with
an uncertain malignant potential despite their small size. There are limited data about driver …

Immunophenotypic and molecular characterization of pancreatic neuroendocrine tumors producing serotonin

T Depoilly, R Leroux, D Andrade, R Nicolle… - Modern …, 2022 - nature.com
Serotonin producing pancreatic neuroendocrine tumors (SP-PanNET) account for 0.58–
1.4% of all pancreatic neuroendocrine tumors (PanNET). They may present with atypical …

Gastro-entero-pancreatic neuroendocrine neoplasia: The rules for non-operative management

F Panzuto, S Massironi, S Partelli, D Campana… - Surgical Oncology, 2020 - Elsevier
Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) with favorable
pathological and clinical features may be considered as indolent lesions, and therefore be …

[HTML][HTML] Current screening strategies for pancreatic cancer

P Vanek, O Urban, V Zoundjiekpon, P Falt - Biomedicines, 2022 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC) is a dreaded malignancy with a dismal 5-year
survival rate despite maximal efforts on optimizing treatment strategies. Radical surgery is …

Spatial and temporal heterogeneity of digestive neuroendocrine neoplasms

P Bourdeleau, A Couvelard, M Ronot… - Therapeutic …, 2023 - journals.sagepub.com
Neuroendocrine neoplasms (NENs) are initially monoclonal neoplasms that progressively
become polyclonal, with very different genotypic and phenotypic characteristics leading to …

Molecular profile of pancreatic neuroendocrine neoplasms (PanNENs): Opportunities for personalized therapies

J Arakelyan, D Zohrabyan, PA Philip - Cancer, 2021 - Wiley Online Library
Pancreatic neuroendocrine neoplasms (panNENs) are the second most common epithelial
tumors of the pancreas. Despite improvements in prognostic grading and staging systems, it …

Detecting somatic mutations for well-differentiated pancreatic neuroendocrine tumors in endoscopic ultrasound-guided fine needle aspiration with next-generation …

EM Ghabi, JR Habib, S Shoucair, AA Javed… - Annals of surgical …, 2023 - Springer
Abstract Background Pancreatic neuroendocrine tumors (PanNETs) exhibit heterogenous
behavior, whereby some small tumors are aggressive with a propensity for metastasis …

Recurring pancreatic neuroendocrine tumor: timing and pattern of recurrence and current treatment

A Pulvirenti, AA Javed, T Michelakos… - Annals of …, 2023 - journals.lww.com
Objective: The objective of this study was to describe the pattern of recurrence, treatments
received, as well the oncological outcomes, of pancreatic neuroendocrine tumors …

[HTML][HTML] Telomere length alterations and ATRX/DAXX loss in pituitary adenomas

CM Heaphy, WL Bi, S Coy, C Davis, GL Gallia… - Modern Pathology, 2020 - Elsevier
Telomeres are nucleoprotein complexes located at the termini of eukaryotic chromosomes
that prevent exonucleolytic degradation and end-to-end chromosomal fusions. Cancers …

Surgical principles in the management of pancreatic neuroendocrine neoplasms

V Andreasi, F Muffatti, G Guarneri, M Falconi… - … Treatment Options in …, 2020 - Springer
Opinion statement Pancreatic neuroendocrine neoplasms (PanNENs) are increasingly
recognized entities, whose incidence has dramatically grown during the last two decades …