Introduction: Recent studies have suggested that alternative lengthening of telomeres (ALT)
is associated with metastasis and poor survival in pancreatic neuroendocrine tumors …

Abstract Pancreatic Neuroendocrine Neoplasms (PanNENs) comprise a rare and
heterogeneous group of tumors derived from neuroendocrine cells of the pancreas. Despite …

In the past 20 years there have been great advances in our understanding of the molecular
genetics of gastrointestinal tumors. In general, cancers develop and proliferate due to: driver …

Background The occurrence of liver metastasis in pancreatic neuroendocrine tumor (pNET)
after primary site surgery significantly hampers the improvement of patient's overall survival …

Many exciting advances in cancer-related telomere biology have been made in the past
decade. Of these recent advances, great progress has also been made with respect to the …

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive disease with high mortality
rates due to late diagnosis and rapid progression. Therefore, better tools for earlier detection …

Včasná detekce karcinomu pankreatu je považována za nejúčinnější způsob, jak zvýšit míru
přežití u pacientů s tímto onemocněním. Jedinci s familiárním výskytem nebo syndromy …

In the present issue of Digestive and Liver Disease, Pr Falconi's team raises interesting
questions in its article “The Size of Well Differentiated Pancreatic Neuroendocrine Tumours …

Pancreatic neuroendocrine neoplasm (pNEN) is highly heterogeneous. Surgery is an
important part of the comprehensive treatment for pNEN, however, the low incidence and …

Neuroendocrine tumors (NETs) are largely heterogeneous, featuring different sites of origin,
biological behavior, and malignant potential. Diagnosis and prognostic stratification of these …