Microglia polarization from M1 to M2 in neurodegenerative diseases

S Guo, H Wang, Y Yin - Frontiers in aging neuroscience, 2022 - frontiersin.org
Microglia-mediated neuroinflammation is a common feature of neurodegenerative diseases
such as Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis …

Nanozymes-recent development and biomedical applications

X Ren, D Chen, Y Wang, H Li, Y Zhang, H Chen… - Journal of …, 2022 - Springer
Nanozyme is a series of nanomaterials with enzyme-mimetic activities that can proceed with
the catalytic reactions of natural enzymes. In the field of biomedicine, nanozymes are …

Superoxide dismutase nanozymes: an emerging star for anti-oxidation

H Zhao, R Zhang, X Yan, K Fan - Journal of Materials Chemistry B, 2021 - pubs.rsc.org
Superoxide dismutases (SODs) are a group of metalloenzymes that catalyze the dismutation
of superoxide radicals (O2˙−) into hydrogen peroxide (H2O2) and oxygen (O2). As the first …

Nanozymes: activity origin, catalytic mechanism, and biological application

W Yang, X Yang, L Zhu, H Chu, X Li, W Xu - Coordination Chemistry …, 2021 - Elsevier
Nanozymes are nanomaterials with excellent enzyme-like characteristics. Compared with
natural enzymes, nanozymes possess significant advantages, such as low cost, high …

Neutrophil-like cell-membrane-coated nanozyme therapy for ischemic brain damage and long-term neurological functional recovery

L Feng, C Dou, Y Xia, B Li, M Zhao, P Yu, Y Zheng… - ACS …, 2021 - ACS Publications
Oxidative stress and a series of excessive inflammatory responses are major obstacles for
neurological functional recovery after ischemic stroke. Effective noninvasive anti …

Defect‐rich adhesive molybdenum disulfide/rGO vertical heterostructures with enhanced nanozyme activity for smart bacterial killing application

L Wang, F Gao, A Wang, X Chen, H Li… - Advanced …, 2020 - Wiley Online Library
Nanomaterials with intrinsic enzyme‐like activities, namely “nanozymes,” are showing
increasing potential as a new type of broad‐spectrum antibiotics. However, their feasibility is …

Multi-enzyme activity nanozymes for biosensing and disease treatment

L Su, S Qin, Z Xie, L Wang, K Khan, AK Tareen… - Coordination Chemistry …, 2022 - Elsevier
In cells, multi-step biochemical reactions catalyzed by multi-enzyme biocatalysts are critical.
While, multi-enzyme biocatalysts have evolved to catalyze these diverse reactions in …

Nanozymes for regenerative medicine

X Mou, Q Wu, Z Zhang, Y Liu, J Zhang, C Zhang… - Small …, 2022 - Wiley Online Library
Nanozymes refer to nanomaterials that catalyze enzyme substrates into products under
relevant physiological conditions following enzyme kinetics. Compared to natural enzymes …

Injectable Hydrogel Based on Defect‐Rich Multi‐Nanozymes for Diabetic Wound Healing via an Oxygen Self‐Supplying Cascade Reaction

Y Li, R Fu, Z Duan, C Zhu, D Fan - Small, 2022 - Wiley Online Library
Diabetic wound healing remains challenging owing to the risk for bacterial infection,
hypoxia, excessive glucose levels, and oxidative stress. Glucose‐activated cascade …

Antioxidant and Prooxidant Nanozymes: From Cellular Redox Regulation to Next‐Generation Therapeutics

N Singh, GR Sherin, G Mugesh - Angewandte Chemie, 2023 - Wiley Online Library
Nanozymes, nanomaterials with enzyme‐mimicking activity, have attracted tremendous
interest in recent years owing to their ability to replace natural enzymes in various …