Glycosylation is a prevalent, yet heterogeneous modification with a broad range of
implications in molecular biology. This heterogeneity precludes enrichment strategies that …

Facilitated by advances in the separation sciences, mass spectrometry and informatics,
glycoproteomics, the analysis of intact glycopeptides at scale, has recently matured enabling …

Site-specific characterization of glycosylation requires intact glycopeptide analysis, and
recent efforts have focused on how to best interrogate glycopeptides using tandem mass …

As the body fluid that directly interchanges with the extracellular fluid of the central nervous
system (CNS), cerebrospinal fluid (CSF) serves as a rich source for CNS-related disease …

Glycopeptides in peptide or digested protein samples pose a number of analytical and
bioinformatics challenges beyond those posed by unmodified peptides or peptides with …

Site-specific O-glycoproteome mapping in complex biological systems provides a molecular
basis for understanding the structure–function relationships of glycoproteins and their roles …

Biological processes unfold across broad spatial and temporal dimensions, and
measurement of the underlying molecular world is essential to their understanding …

Due to their involvement in numerous biochemical pathways, neuropeptides have been the
focus of many recent research studies. Unfortunately, classic analytical methods, such as …

Glycosylated neuropeptides were recently discovered in crustaceans, a model organism
with a well‐characterized neuroendocrine system. Several workflows exist to characterize …

O-GlcNAc is a pleotropic, enigmatic post-translational modification (PTM). This PTM modifies
thousands of proteins differentially across tissue types and regulates diverse cellular …