Exosomes are cell–cell communicators emerging as a new paradigm for noninvasive
diagnosis and prognosis of treatment response. Exosomal tetraspanin proteins like CD63 …

Migrasomes are migration‐dependent membrane‐bound vesicular structures that contain
cellular contents and small vesicles. Migrasomes grow on the tips or intersections of the …

Exosomes from mesenchymal stem cells have been widely studied as therapeutics to treat
myocardial infarction. However, exosomes injected for therapeutic purposes face a number …

Background At present, patients with myocardial infarction remain an increased risk for
myocardial ischemia/reperfusion injury (MI/RI). There lacks effectively method to treat MI/RI …

CD9, a 24 kDa tetraspanin membrane protein, is known to regulate cell adhesion and
migration, cancer progression and metastasis, immune and allergic responses, and viral …

Cell migration plays a critical role in vascular homeostasis. Under noxious stimuli,
endothelial cells (ECs) migration always contributes to vascular repair, while enhanced …

Tetraspanins comprise a family of proteins embedded in the membrane through four
transmembrane domains. One of the most distinctive features of tetraspanins is their ability …

Tetraspanins have gained increased attention due to their functional versatility. But the
universal cellular mechanism that governs such versatility remains unknown. Herein we …

Abstract Background The tetraspanins Tspan8 and CD151 promote metastasis, exosomes
(Exo) being suggested to be important in the crosstalk between tumor and host. The …

CD36 is a type 2 scavenger receptor with multiple functions. CD36 binding to oxidized LDL
triggers signaling cascades that are required for macrophage foam cell formation, but the …