Engineering Matrix-Free Drug Protein Nanoparticles with Promising Penetration through Biobarriers for Treating Corneal Neovascularization

H Xu, B Mao, S Ni, X Xie, S Tang, Y Wang, X Zan… - ACS …, 2024 - ACS Publications
Protein drugs have been widely used in treating various clinical diseases because of their
high specificity, fewer side effects, and favorable therapeutic effect, but they greatly suffer …

The capabilities of nanoelectronic 2-D materials for bio-inspired computing and drug delivery indicate their significance in modern drug design

P Hassanzadeh - Life Sciences, 2021 - Elsevier
Remarkable advancements in the computational techniques and nanoelectronics have
attracted considerable interests for development of highly-sophisticated materials (Ms) …

Innovative strategies for drug delivery to the ocular posterior segment

A Gabai, M Zeppieri, L Finocchio, C Salati - Pharmaceutics, 2023 - mdpi.com
Innovative and new drug delivery systems (DDSs) have recently been developed to vehicle
treatments and drugs to the ocular posterior segment and the retina. New formulations and …

Design of an L-valine-modified nanomicelle-based drug delivery system for overcoming ocular surface barriers

H Wu, Y Xu, M Cai, L You, J Liu, X Dong, X Yin, J Ni… - Pharmaceutics, 2022 - mdpi.com
The incidence of ocular surface disease (OSD) is increasing, with a trend towards younger
ages. However, it is difficult for drugs to reach the deep layers of the cornea due to ocular …

Recent Updates on Nanocarriers for Drug Delivery in Posterior Segment Diseases with Emphasis on Diabetic Retinopathy

R Parashar, A Vyas, AK Sah, N Hemnani… - Current Diabetes …, 2024 - ingentaconnect.com
In recent years, various conventional formulations have been used for the treatment and/or
management of ocular medical conditions. Diabetic retinopathy, a microvascular disease of …

Layered Double Hydroxides: Recent Progress and Promising Perspectives Toward Biomedical Applications

L Li, I Soyhan, E Warszawik, P van Rijn - Advanced Science, 2024 - Wiley Online Library
Layered double hydroxides (LDHs) have been widely studied for biomedical applications
due to their excellent properties, such as good biocompatibility, degradability, interlayer ion …

Layered Double Hydroxide Nanomaterials: Biomedical Applications, Current Status and Challenges

R Sharma, Bhawna, S Kumar, P Singh, A Gupta… - Nano Life, 2021 - World Scientific
Layered double hydroxide nanomaterials (LDH NMs) have been dragging the researchers'
attention toward biomedical applications owing to their physiochemical properties …

Engineering of hybrid anticancer drug-loaded polymeric nanoparticles delivery system for the treatment and care of lung cancer therapy

Y Zhao, K Liu, J Li, J Liao, L Ma - Drug Delivery, 2021 - Taylor & Francis
Chemotherapy with combination drugs has become one of the most commonly used cancer
prevention treatments, with positive clinical results. The goal of this study was to develop …

Facile preparation of a pH-sensitive biocompatible nanocarrier based on magnetic layered double hydroxides/Cu MOFs-chitosan crosslinked к-carrageenan for …

A Taghikhani, M Babazadeh, E Ghasemi - Colloids and Surfaces B …, 2024 - Elsevier
Recently, the biocompatibility of hydrogel nanoparticles has gained considerable research
attention in the field of drug delivery. In this regard, we design a pH-controlled nanocarrier …

Synthesis and properties of new multilayer chitosan@ layered double hydroxide/drug loaded phospholipid bilayer nanocomposite bio-hybrids

DA Lerner, S Bégu, A Aubert-Pouëssel, R Polexe… - Materials, 2020 - mdpi.com
A novel bio-hybrid drug delivery system was obtained involving a Mg/Al-NO3 layered double
hydroxide (LDH) intercalated either with ibuprofenate anions (IBU) or a phospholipid bilayer …