Abstract Glutathione S‑transferase Pi (GSTP1) is an isozyme encoded by the GST pi gene
that plays an important regulatory role in detoxification, anti‑oxidative damage, and the …

Prostate cancer (PC) is the most commonly diagnosed neoplasm and the third most
common cause of cancer-related death amongst men in the Western world. PC is a clinically …

Abnormal DNA methylation is an important epigenetic regulator involving tumorigenesis.
Deciphering cancer common and specific DNA methylation patterns is essential for us to …

Purpose Diagnostic and prognostic tools for prostate cancer (PC) are suboptimal, causing
overtreatment of indolent PC and risk of delayed treatment of aggressive PC. Here, we …

GSTP1 belongs to the GSTs family, a group of enzymes involved in detoxification of
exogenous substances and it also plays an important role in cell cycle regulation. Its …

Simple Summary The aim of this review is to evaluate the present status of the use of cell-
free DNA and its fraction of circulating tumor DNA (ctDNA) because this year July 2022, an …

Purpose: Available tools for prostate cancer diagnosis and prognosis are suboptimal and
novel biomarkers are urgently needed. Here, we investigated the regulation and biomarker …

Current diagnostic and prognostic tools for prostate cancer (PC) are suboptimal, leading to
overdiagnosis and overtreatment. Aberrant promoter hypermethylation of specific genes has …

Background: We analysed critically the potential usefulness of RNA-and DNA-based
biomarkers in supporting conventional histological diagnostic tests for prostate carcinoma …

Prostate cancer is the most inheritable cancer with approximately 42% of disease risk
attributed to inherited factors by studies of twins, indicating the importance of additional …