Mammalian oocytes can reprogram differentiated somatic cells into a totipotent state through
somatic cell nuclear transfer (SCNT), which is known as cloning. Although many mammalian …

The biology of preimplantation embryo gene expression began 56 years ago with studies of
the effects of protein synthesis inhibition and discovery of changes in embryo metabolism …

Purpose Despite advances in the composition of defined embryo culture media, co-culture
with somatic cells is still used for bovine in vitro embryo production (IVEP) in many …

DNA methylation and histone deacetylation play important roles in the occurrence and
development of cancers by inactivating the expression of tumor suppressors, including …

Key message Improving pollen embryogenesis. Abstract Despite the agro-economic
importance of pollen embryogenesis, the mechanisms underlying this process are still …

Although somatic cell nuclear transfer (SCNT) can be used to create transgenic pigs for
human xenotransplantation, low efficiency limits its use. Trichostatin A (TSA) promotes …

Histone deacetylases (HDACs) catalyze deacetylation of histones that results in altered
transcriptional activity. Inhibitors of HDACs have been shown to induce transcriptional …

The goal of this study was to improve the development of bovine somatic‐cell nuclear
transfer (SCNT) embryos by optimizing the combination of DNA methyltransferases inhibitor …

Methyl-CpG-binding domain protein 3 (MBD3) is a core component of the nucleosome
remodeling and deacetylase (NuRD) complex, which is crucial for pluripotent stem cell …

Contents Somatic cell nuclear transfer (SCNT) is considered as the technique in which a
somatic cell is introduced into an enucleated oocyte to make a cloned animal. However, it is …