Physiological adaptations to weight loss and factors favouring weight regain

FL Greenway - International journal of obesity, 2015 - nature.com
Obesity is a major global health problem and predisposes individuals to several
comorbidities that can affect life expectancy. Interventions based on lifestyle modification (for …

Biology's response to dieting: the impetus for weight regain

PS MacLean, A Bergouignan… - American Journal …, 2011 - journals.physiology.org
Dieting is the most common approach to losing weight for the majority of obese and
overweight individuals. Restricting intake leads to weight loss in the short term, but, by itself …

The defence of body weight: a physiological basis for weight regain after weight loss

P Sumithran, J Proietto - Clinical Science, 2013 - portlandpress.com
Although weight loss can usually be achieved by restricting food intake, the majority of
dieters regain weight over the long-term. In the hypothalamus, hormonal signals from the …

Understanding and addressing the epidemic of obesity: an energy balance perspective

JO Hill - Endocrine reviews, 2006 - academic.oup.com
The intent of this paper is to address the obesity epidemic, which is a term used to describe
the sudden and rapid increase in obesity rates that began in the 1980s and continues …

[图书][B] Handbook of Obesity--Volume 1: Epidemiology, Etiology, and Physiopathology

GA Bray - 2014 - books.google.com
In recent years, we've developed a much better grasp of the biological and other factors
associated with the development of obesity. Reflecting our evolving understanding of …

Metabolic imprinting: critical impact of the perinatal environment on the regulation of energy homeostasis

BE Levin - … Transactions of the Royal Society B …, 2006 - royalsocietypublishing.org
Epidemiological studies in humans suggest that maternal undernutrition, obesity and
diabetes during gestation and lactation can all produce obesity in offspring. Animal models …

Constant vigilance: The impact of weight stigma, vigilance, and internalization on maladaptive eating behaviors.

KE Wetzel, MS Himmelstein - Health Psychology, 2023 - psycnet.apa.org
Objective: Weight stigma (social devaluation because of weight) and weight bias
internalization (self-stigma due to weight) have been independently implicated in …

Mechanisms of weight regain following weight loss

ES Blomain, DA Dirhan, MA Valentino… - International …, 2013 - Wiley Online Library
Obesity is a world‐wide pandemic and its incidence is on the rise along with associated
comorbidities. Currently, there are few effective therapies to combat obesity. The use of …

Clinical significance of adaptive thermogenesis

GC Major, E Doucet, P Trayhurn, A Astrup… - International journal of …, 2007 - nature.com
The epidemic of obesity is developing faster than the scientific understanding of an efficient
way to overcome it, as reflected by the low success rate of short-and long-term weight loss …

[HTML][HTML] Obesogenic memory can confer long-term increases in adipose tissue but not liver inflammation and insulin resistance after weight loss

J Schmitz, N Evers, M Awazawa, HT Nicholls… - Molecular …, 2016 - Elsevier
Objective Obesity represents a major risk factor for the development of type 2 diabetes
mellitus, atherosclerosis and certain cancer entities. Treatment of obesity is hindered by the …