The common histones H2A, H2B, H3, and H4 are the characteristic components of
eukaryotic nucleosomes, which function to wrap DNA and compact the genome as well as to …

Exchanging core histones in the nucleosome for paralogous variants can have important
functional ramifications. Many of these variants, and their physiological roles, have been …

CRISPR–Cas systems provide heritable immunity against viruses and other mobile genetic
elements by incorporating fragments of invader DNA into the host CRISPR array as spacers …

Genome regulation in eukaryotes revolves around the nucleosome, the fundamental
building block of eukaryotic chromatin. Its constituent parts, the four core histones (H3, H4 …

Many archaea encode and express histone proteins to compact their genomes. Archaeal
and eukaryotic histones share a near-identical fold that permits DNA wrapping through …

The latest Virtual Issue from Genome Biology and Evolution highlights articles that provide
new insight into the deep evolutionary relationships among extant organisms and the origin …