Today, magnetic cell sorting and flow cytometric cell sorting both are state‐of‐the‐art
technologies, with a plethora of applications in biology and biomedicine. Both technologies …

Circular RNA (circRNAs) is a covalently closed circular non-coding RNA formed by reverse
back-splicing from precursor messenger RNA. It is found widely in eukaryotic cells and can …

The direct detection of antigen-specific T cells using tetramers of soluble peptide–major
histocompatibilty complex (pMHC) molecules is widely used in both basic and clinical …

Labelling antigen-specific T cells with peptide–MHC multimers has provided an invaluable
way to monitor T cell-mediated immune responses. A number of recent developments in this …

Book Cover Legend Upper left panel: Receiver operating characteristic (ROC) curve,
indicating the diagnostic sensitivity and specificity of total PSA (PSA-T), the combination of …

Abstract CD8+ tumor-infiltrating lymphocytes (TIL) lack in vivo and in vitro lytic function due
to a signaling deficit characterized by failure to flux calcium or activate tyrosine kinase …

The past few years have seen significant progress towards understanding the mechanisms
of immune surveillance and inflammation in the nervous system. In this review, the …

There is a clear decrease in CD8+ T cell effector function with aging, a loss once thought to
be intrinsic to the CD8+ T cells. Recent studies suggest, however, that this decline may be a …

The T cell receptor (TCR) interacts with peptide-major histocompatibility complex (pMHC) to
enable T cell development and trigger adaptive immune responses. For this reason, TCR …

The development of immune monitoring assays is essential to determine the immune
responses against tumor‐specific antigens (TSAs) and tumor‐associated antigens (TAAs) …