Circulating biomarkers in the diagnosis and management of hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is one of the most prevalent and lethal causes of cancer-
related death worldwide. The treatment of HCC remains challenging and is largely …
related death worldwide. The treatment of HCC remains challenging and is largely …
Monitoring and adapting cancer treatment using circulating tumor DNA kinetics: Current research, opportunities, and challenges
Circulating tumor DNA (ctDNA) has emerged as a biomarker with wide-ranging applications
in cancer management. While its role in guiding precision medicine in certain tumors via …
in cancer management. While its role in guiding precision medicine in certain tumors via …
Circulating tumor DNA and minimal residual disease (MRD) in solid tumors: current horizons and future perspectives
Y Peng, W Mei, K Ma, C Zeng - Frontiers in oncology, 2021 - frontiersin.org
Circulating tumor DNA (ctDNA) is cell-free DNA (cfDNA) fragment in the bloodstream that
originates from malignant tumors or circulating tumor cells. Recently, ctDNA has emerged as …
originates from malignant tumors or circulating tumor cells. Recently, ctDNA has emerged as …
[HTML][HTML] Cost-of-illness studies: concepts, scopes, and methods
C Jo - Clinical and molecular hepatology, 2014 - ncbi.nlm.nih.gov
Liver diseases are one of the main causes of death, and their ever-increasing prevalence is
threatening to cause significant damage both to individuals and society as a whole. This …
threatening to cause significant damage both to individuals and society as a whole. This …
Liquid biopsy in the clinical management of hepatocellular carcinoma
J von Felden, T Garcia-Lezana, K Schulze, B Losic… - Gut, 2020 - gut.bmj.com
With increasing knowledge on molecular tumour information, precision oncology has
revolutionised the medical field over the past years. Liquid biopsy entails the analysis of …
revolutionised the medical field over the past years. Liquid biopsy entails the analysis of …
Personalized neoantigen vaccine prevents postoperative recurrence in hepatocellular carcinoma patients with vascular invasion
Z Cai, X Su, L Qiu, Z Li, X Li, X Dong, F Wei, Y Zhou… - Molecular Cancer, 2021 - Springer
Background Clinically, prophylactic anti-recurrence treatments for hepatocellular carcinoma
(HCC) patients after radical surgery are extremely limited. Neoantigen based vaccine can …
(HCC) patients after radical surgery are extremely limited. Neoantigen based vaccine can …
[HTML][HTML] Cellular heterogeneity and plasticity in liver cancer
LK Chan, YM Tsui, DWH Ho, IOL Ng - Seminars in cancer biology, 2022 - Elsevier
Hepatocarcinogenesis involves complex genetic and cellular dysregulations which drive the
formation of hepatocellular carcinoma (HCC), the predominant form of primary liver cancer …
formation of hepatocellular carcinoma (HCC), the predominant form of primary liver cancer …
[HTML][HTML] Circulating tumor DNA as an emerging liquid biopsy biomarker for early diagnosis and therapeutic monitoring in hepatocellular carcinoma
X Wu, J Li, A Gassa, D Buchner, H Alakus… - … journal of biological …, 2020 - ncbi.nlm.nih.gov
As one of the most common malignant tumors worldwide, hepatocellular carcinoma (HCC) is
known for its poor prognosis due to diagnosis only in advanced stages. Nearly 50% of the …
known for its poor prognosis due to diagnosis only in advanced stages. Nearly 50% of the …
[HTML][HTML] The molecular profiling of solid tumors by liquid biopsy: A position paper of the AIOM–SIAPEC-IAP–SIBioC–SIC–SIF Italian Scientific Societies
A Russo, L Incorvaia, M Del Re, U Malapelle… - ESMO open, 2021 - Elsevier
The term liquid biopsy (LB) refers to the use of various biological fluids as a surrogate for
neoplastic tissue to achieve information for diagnostic, prognostic and predictive purposes …
neoplastic tissue to achieve information for diagnostic, prognostic and predictive purposes …
Utility of liquid biopsy analysis in detection of hepatocellular carcinoma, determination of prognosis, and disease monitoring: a systematic review
Background & Aims Liquid biopsies, or blood samples, can be analyzed to detect circulating
tumor cells (CTCs), cell-free DNA (cfDNA), and extracellular vesicles, which might identify …
tumor cells (CTCs), cell-free DNA (cfDNA), and extracellular vesicles, which might identify …