Applications of whole-cell matrix-assisted laser-desorption/ionization time-of-flight mass spectrometry in systematic microbiology

M Welker, ERB Moore - Systematic and applied microbiology, 2011 - Elsevier
In the last few years matrix assisted laser desorption/ionization time-of-flight mass
spectrometry (MALDI-TOF MS) has been increasingly studied and applied for the …

Streptococcus mitis: walking the line between commensalism and pathogenesis

J Mitchell - Molecular oral microbiology, 2011 - Wiley Online Library
Streptococcus mitis is a viridans streptococcus and a normal commensal of the human
oropharynx. However, S. mitis can escape from this niche and cause a variety of infectious …

Oligotyping analysis of the human oral microbiome

AM Eren, GG Borisy, SM Huse… - Proceedings of the …, 2014 - National Acad Sciences
The Human Microbiome Project provided a census of bacterial populations in healthy
individuals, but an understanding of the biomedical significance of this census has been …

[HTML][HTML] Diversification of bacterial genome content through distinct mechanisms over different timescales

NJ Croucher, PG Coupland, AE Stevenson… - Nature …, 2014 - nature.com
Bacterial populations often consist of multiple co-circulating lineages. Determining how such
population structures arise requires understanding what drives bacterial diversification …

Molecular mechanisms of β-lactam resistance in Streptococcus pneumoniae

R Hakenbeck, R Brückner, D Denapaite… - Future …, 2012 - Future Medicine
Alterations in the target enzymes for β-lactam antibiotics, the penicillin-binding proteins
(PBPs), have been recognized as a major resistance mechanism in Streptococcus …

Proteomics for routine identification of microorganisms

M Welker - Proteomics, 2011 - Wiley Online Library
The invention of MALDI‐TOF‐MS enormously contributed to the understanding of protein
chemistry and cell biology. Without this technique proteomics would most likely not be the …

[HTML][HTML] Streptococcus mitis strains causing severe clinical disease in cancer patients

SA Shelburne, P Sahasrabhojane… - Emerging infectious …, 2014 - ncbi.nlm.nih.gov
The genetically diverse viridans group streptococci (VGS) are increasingly recognized as
the cause of a variety of human diseases. We used a recently developed multilocus …

[HTML][HTML] The use of bacteriophages to biocontrol oral biofilms

SP Szafrański, A Winkel, M Stiesch - Journal of biotechnology, 2017 - Elsevier
Infections induced by oral biofilms include caries, as well as periodontal, and peri-implant
disease, and may influence quality of life, systemic health, and expenditure. As bacterial …

[HTML][HTML] Extrachromosomal and mobile elements in enterococci: transmission, maintenance, and epidemiology

DB Clewell, KE Weaver, GM Dunny… - … : From commensals to …, 2014 - ncbi.nlm.nih.gov
Extrachromosomal elements are ubiquitous in the prokaryotic world and play important roles
in the adaptation and survival of cell populations, especially in changing environments …

Parallel evolution of Streptococcus pneumoniae and Streptococcus mitis to pathogenic and mutualistic lifestyles

M Kilian, DR Riley, A Jensen, H Brüggemann… - MBio, 2014 - Am Soc Microbiol
The bacterium Streptococcus pneumoniae is one of the leading causes of fatal infections
affecting humans. Intriguingly, phylogenetic analysis shows that the species constitutes one …