For more than half a century, cytotoxic agents have been investigated as a possible
treatment for cancer. Research on animal venoms has revealed their high toxicity on tissues …

Envenomations due to snake bites are commonly treated by parenteral administration of
horse or sheep-derived polyclonal antivenoms aimed at the neutralization of toxins …

Background Snakebite in India results in over 58,000 fatalities and a vast number of
morbidities annually. The majority of these clinically severe envenomings are attributed to …

Revised and updated, Chemical Reagents for Protein Modification, Third Edition is an
encyclopedic work describing the many approaches to the site-specific modification of …

Background Gene duplication followed by functional divergence has long been
hypothesized to be the main source of molecular novelty. Convincing examples of …

Many plants are used in traditional medicine as active agents against various effects
induced by snakebite. The methanolic extract from Cordia verbenacea (Cv) significantly …

Abstract Phospholipases A2 (PLA2s) are abundant components in snake venoms, which
play important toxic roles. This review focuses on group II PLA2s endowed with myotoxic …

Two subtypes of phospholipases A2 (PLA2s) with the ability to induce myonecrosis,'Asp49'
and 'Lys49'myotoxins, often coexist in viperid snake venoms. Since the latter lack catalytic …

This paper reports the purification and biochemical/pharmacological characterization of two
myotoxic phospholipases A2 (PLA2s) from Bothrops brazili venom, a native snake from …

Phospholipases A2 (PLA2s) are commonly found in snake venoms from Viperidae,
Hydrophidae and Elaphidae families and have been extensively studied due to their …