Immune cell-derived extracellular vesicles–functions and therapeutic applications
RE Veerman, GG Akpinar, M Eldh… - Trends in molecular …, 2019 - cell.com
Extracellular vesicles (EVs) are nano-sized vesicles with the capacity to transfer nucleic
acids, proteins, and lipids, and are released by all cells. EV is an umbrella term for …
acids, proteins, and lipids, and are released by all cells. EV is an umbrella term for …
Neutral sphingomyelinases control extracellular vesicles budding from the plasma membrane
K Menck, C Sönmezer, TS Worst, M Schulz… - Journal of …, 2017 - Taylor & Francis
Extracellular vesicles (EVs) are membrane particles secreted from cells into all body fluids.
Several EV populations exist differing in size and cellular origin. Using differential …
Several EV populations exist differing in size and cellular origin. Using differential …
New insights into extracellular vesicle biogenesis and function
It is becoming increasingly evident that most cell types are capable of forming and releasing
multiple distinct classes of membrane-enclosed packages, referred to as extracellular …
multiple distinct classes of membrane-enclosed packages, referred to as extracellular …
[HTML][HTML] Recent developments in the nomenclature, presence, isolation, detection and clinical impact of extracellular vesicles
E Van der Pol, AN Böing, EL Gool… - Journal of thrombosis and …, 2016 - Elsevier
The research field of extracellular vesicles (EVs), such as microparticles and exosomes, is
growing exponentially. The goal of this review is to provide an overview of recent …
growing exponentially. The goal of this review is to provide an overview of recent …
Extracellular vesicles as next generation immunotherapeutics
Extracellular vesicles (EVs) function as a mode of intercellular communication and
molecular transfer to elicit diverse biological/functional response. Accumulating evidence …
molecular transfer to elicit diverse biological/functional response. Accumulating evidence …
[HTML][HTML] Exosomes and exosomal RNAs in breast cancer: A status update
S Lakshmi, TA Hughes, S Priya - European Journal of Cancer, 2021 - Elsevier
Improved treatment of breast cancer, the world's second most common cancer, requires
identification of new sensitive prognostic and diagnostic biomarkers. Exosomes are lipid …
identification of new sensitive prognostic and diagnostic biomarkers. Exosomes are lipid …
[HTML][HTML] Extracellular vesicles as circulating cancer biomarkers: opportunities and challenges
Extracellular vesicles (EVs) are small, lipid-bound particles containing nucleic acid and
protein cargo which are excreted from cells under a variety of normal and pathological …
protein cargo which are excreted from cells under a variety of normal and pathological …
Exosome miR‐335 as a novel therapeutic strategy in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is a common and deadly cancer. Most cases of HCC arise
in a cirrhotic/fibrotic liver, indicating that environment may play a paramount role in cancer …
in a cirrhotic/fibrotic liver, indicating that environment may play a paramount role in cancer …
[HTML][HTML] Versatile roles of extracellular vesicles in cancer
Numerous studies have shown that non–cell-autonomous regulation of cancer cells is an
important aspect of tumorigenesis. Cancer cells need to communicate with stromal cells by …
important aspect of tumorigenesis. Cancer cells need to communicate with stromal cells by …
SCS macrophages suppress melanoma by restricting tumor-derived vesicle–B cell interactions
Tumor-derived extracellular vesicles (tEVs) are important signals in tumor–host cell
communication, yet it remains unclear how endogenously produced tEVs affect the host in …
communication, yet it remains unclear how endogenously produced tEVs affect the host in …