Dietary modification is central to obesity treatment. Weight loss diets are available that
include various permutations of energy restriction, macronutrients, foods, and dietary intake …

Elevated levels of diastolic BP and especially systolic BP (SBP) are major risk factors for the
development of HF. 18, 19 One of the most impactful observations from the Framingham …

Objective Development of these guidelines is mandated by the American Association of
Clinical Endocrinologists (AACE) Board of Directors and the American College of …

Summary Background Findings from the Look AHEAD trial showed no significant reductions
in the primary outcome of cardiovascular disease incidence in adults with type 2 diabetes …

OBJECTIVE Type 2 diabetes mellitus (T2DM) is generally regarded as an irreversible
chronic condition. Because a very low-calorie diet (VLCD) can bring about acute return to …

Background Weight loss is recommended for overweight or obese patients with type 2
diabetes on the basis of short-term studies, but long-term effects on cardiovascular disease …

The long-term weight management of obesity remains a very difficult task, associated with a
high risk of failure and weight regain. However, many people report that they have …

OBJECTIVE The overall aim of the Alliance of Randomized Trials of Medicine versus
Metabolic Surgery in Type 2 Diabetes (ARMMS-T2D) consortium is to assess the durability …

The beneficial effects of physical activity (PA) are well documented, yet the mechanisms by
which PA prevents disease and improves health outcomes are poorly understood. To …

Objective To evaluate 8‐year weight losses achieved with intensive lifestyle intervention (ILI)
in the Look AHEAD (Action for Health in Diabetes) study. Design and Methods Look AHEAD …