Background A strategy of administering a transfusion only when the hemoglobin level falls
below 7 or 8 g per deciliter has been widely adopted. However, patients with acute …

Background Anemia, characterized by low hemoglobin levels, is a global public health
concern. Anemia is an independent factor worsening outcomes in various patient groups …

Chimeric antigen receptor T-cell (CAR-T) therapy has heralded a new era in the treatment of
various hematological malignancies, increasingly being utilized in earlier lines of therapy …

Importance Tranexamic acid reduces bleeding and blood transfusion in many types of
surgery, but its effect in patients undergoing liver resection for a cancer-related indication …

Background: The optimal hemoglobin threshold to guide red blood cell (RBC) transfusion for
patients with acute myocardial infarction (MI) and anemia is uncertain. Objective: To …

Metformin is a common diabetes drug that may reduce lactate clearance by inhibiting
mitochondrial oxidative phosphorylation, leading to metformin-associated lactic acidosis …

Blood transfusion is firmly established in contemporary medical practice. More than 16
million units are administered each year in the US, 1 cementing its status as one of the most …

Background Transfusion‐related acute lung injury (TRALI) is a leading cause of transfusion‐
related mortality. A concern with passive surveillance to detect transfusion reactions is …

Abstract Aim The “2024 AHA/ACC/ACS/ASNC/HRS/SCA/SCCT/SCMR/SVM Guideline for
Perioperative Cardiovascular Management for Noncardiac Surgery” provides …

Background Approximately 1% to 2% of all hospitalized children receive a transfusion of
blood products, in Germany as in other countries. High-quality scientific evidence on …