Pharmacokinetic evaluation of piperacillin-tazobactam

Y Hayashi, JA Roberts, DL Paterson… - Expert opinion on drug …, 2010 - Taylor & Francis
Importance of the field: Piperacillin-tazobactam is a frequently prescribed intravenous
antibiotic for moderate to severe infections used in hospital settings because of its broad …

First-dose and steady-state population pharmacokinetics and pharmacodynamics of piperacillin by continuous or intermittent dosing in critically ill patients with sepsis

JA Roberts, CMJ Kirkpatrick, MS Roberts… - International journal of …, 2010 - Elsevier
The objectives of this study were (i) to compare the plasma concentration–time profiles for
first-dose and steady-state piperacillin administered by intermittent or continuous dosing to …

Piperacillin penetration into tissue of critically ill patients with sepsis—bolus versus continuous administration?

JA Roberts, MS Roberts, TA Robertson… - Critical care …, 2009 - journals.lww.com
Objective: To describe a pharmacokinetic model of piperacillin concentrations in plasma and
subcutaneous tissue when administered by bolus dosing and continuous infusion in …

[HTML][HTML] Green Bio-Analytical Study of Gabapentin in Human Plasma Coupled with Pharmacokinetic and Bioequivalence Assessment Using UPLC-MS/MS

RM Tony, MA El Hamd, M Gamal, SF Saleh… - Separations, 2023 - mdpi.com
Gabapentin (GAB) is a cyclohexane acetic acid, structurally related to the neurotransmitter
gamma-aminobutyric acid (GABA), and considered the principal inhibitory neurotransmitter …