Post-operative adhesions: a comprehensive review of mechanisms

A Fatehi Hassanabad, AN Zarzycki, K Jeon, JF Deniset… - Biomedicines, 2021 - mdpi.com
Post-surgical adhesions are common in almost all surgical areas and are associated with
significant rates of morbidity, mortality, and increased healthcare costs, especially when a …

Postoperative peritoneal adhesion: an update on physiopathology and novel traditional herbal and modern medical therapeutics

S Soltany - Naunyn-Schmiedeberg's Archives of Pharmacology, 2021 - Springer
Postoperative peritoneal adhesion (PPA) is a serious clinical condition that affects the high
percentage of patients after abdominal surgery. In this review, we have tried to focus on …

An injectable and rapidly degraded carboxymethyl chitosan/polyethylene glycol hydrogel for postoperative antiadhesion

M Wang, S Lin, M Liu, J Jiao, H Mi, J Sun, Y Liu… - Chemical Engineering …, 2023 - Elsevier
Postoperative peritoneal adhesion will result in serious complications for patients and
increase their hospitalization costs. The critical period for postoperative adhesion formation …

[HTML][HTML] Bottlebrush inspired injectable hydrogel for rapid prevention of postoperative and recurrent adhesion

J Gao, J Wen, D Hu, K Liu, Y Zhang, X Zhao, K Wang - Bioactive Materials, 2022 - Elsevier
Postsurgical adhesion is a common clinic disease induced by surgical trauma,
accompanying serious subsequent complications. Current non-surgical approaches of …

An injectable and antifouling self-fused supramolecular hydrogel for preventing postoperative and recurrent adhesions

X Zhao, J Yang, Y Liu, J Gao, K Wang, W Liu - Chemical Engineering …, 2021 - Elsevier
Abdominal adhesions is a type of serious complication of abdominal surgery. Existing
barrier hydrogels are severely limited in the prevention of adhesions due to their poor …

Hypoxia, cytokines and stromal recruitment: parallels between pathophysiology of encapsulating peritoneal sclerosis, endometriosis and peritoneal metastasis

RB Wilson - Pleura and peritoneum, 2018 - degruyter.com
Peritoneal response to various kinds of injury involves loss of peritoneal mesothelial cells
(PMC), danger signalling, epithelial-mesenchymal transition and mesothelial-mesenchymal …

Anti-interleukin-6 receptor antibody treatment ameliorates postoperative adhesion formation

N Uyama, H Tsutsui, S Wu, K Yasuda, E Hatano… - Scientific reports, 2019 - nature.com
Postoperative adhesion formation often ruins the quality of life or is an obstacle to illnesses
with curative operation such as cancer. Previously we demonstrated that interferon-γ …

Integration of exosomal miR-106a and mesothelial cells facilitates gastric cancer peritoneal dissemination

M Zhu, N Zhang, J Ma, S He - Cellular Signalling, 2022 - Elsevier
Background Metastatic organotropism is considered the end stage of malignancy with the
mechanism still have some mysteries that have not been disclosed. Although the role of miR …

Reprogramming of mesothelial-mesenchymal transition in chronic peritoneal diseases by estrogen receptor modulation and TGF-β1 inhibition

RB Wilson, R Archid, MA Reymond - International Journal of Molecular …, 2020 - mdpi.com
In chronic peritoneal diseases, mesothelial-mesenchymal transition is determined by cues
from the extracellular environment rather than just the cellular genome. The transformation …

Peripheral serotonin regulates postoperative intra-abdominal adhesion formation in mice

J Bi, S Zhang, Z Du, J Zhang, Y Deng, C Liu… - Scientific Reports, 2017 - nature.com
The aim of the present study is to investigate the role and potential mechanisms of
peripheral serotonin in postoperative intra-abdominal adhesion formation in mice. The …