Pharmacogenomics: biomarker-directed therapy for bladder cancer

RT Jones, KM Felsenstein… - Urologic Clinics, 2016 - urologic.theclinics.com
It is estimated that 74,000 people in the United States and roughly 386,000 people globally
will be newly diagnosed with bladder cancer in 2015. 1, 2 Bladder cancer represents a …

An update on treatment of penile cancer

J Chadha, J Chahoud… - Therapeutic Advances in …, 2022 - journals.sagepub.com
Penile cancer is a rare malignancy, particularly in industrialized nations. In the United
States, rates are approximately less than 1 per 100,000 men per year with just over 2000 …

The prognostic role of human papillomavirus and p16 status in penile squamous cell carcinoma—a systematic review

K Parza, A Mustasam, F Ionescu, M Paravathaneni… - Cancers, 2023 - mdpi.com
Simple Summary Penile squamous cell carcinoma (PSCC) is a rare and aggressive cancer.
About half of all PSCC cases are thought to be related to human papillomavirus (HPV) or …

Prognostic significance of HPV and p16 status in men diagnosed with penile cancer: a systematic review and meta-analysis

FL Sand, CL Rasmussen, MH Frederiksen… - … Biomarkers & Prevention, 2018 - AACR
It has been shown that human papillomavirus (HPV) and p16 status has prognostic value in
some HPV-associated cancers. However, studies examining survival in men with penile …

Human papillomavirus

EM Burd, CL Dean - Diagnostic Microbiology of the …, 2016 - Wiley Online Library
Human papillomavirus (HPV), a member of the Papillomaviridae family, is a small (8kb),
nonenveloped, double‐stranded DNA virus. HPV has a predilection for infecting cutaneous …

Genomic profiling of penile squamous cell carcinoma reveals new opportunities for targeted therapy

AS McDaniel, DH Hovelson, AK Cani, CJ Liu, Y Zhai… - Cancer research, 2015 - AACR
Penile squamous cell carcinoma (PeSCCA) is a rare malignancy for which there are limited
treatment options due to a poor understanding of the molecular alterations underlying …

Two major pathways of penile carcinogenesis: HPV-induced penile cancers overexpress p16ink4a, HPV-negative cancers associated with dermatoses express p53 …

S Mannweiler, S Sygulla, E Winter… - Journal of the American …, 2013 - Elsevier
BACKGROUND: Penile squamous cell carcinomas (SCC) arise either through transforming
infections with human papillomavirus (HPV) or independent of HPV, often in the background …

The molecular pathogenesis of penile carcinoma—current developments and understanding

A Emmanuel, J Nettleton, N Watkin, DM Berney - Virchows Archiv, 2019 - Springer
Penile squamous cell carcinoma is a rare malignancy with various distinct histological
subtypes, each with distinct appearances, histotypic specific associations with human …

Immunotherapeutic approaches for the treatment of HPV-associated (pre-) cancer of the cervix, vulva and penis

TS Rafael, J Rotman, OR Brouwer… - Journal of Clinical …, 2022 - mdpi.com
Human papillomavirus (HPV) infection drives tumorigenesis in almost all cervical cancers
and a fraction of vulvar and penile cancers. Due to increasing incidence and low vaccination …

The role of human papilloma virus in urological malignancies

I Heidegger, W Borena, R Pichler - Anticancer research, 2015 - ar.iiarjournals.org
Human papillomavirus (HPV) is associated with cancer of the cervix uteri, penis, vulva,
vagina, anus and oropharynx. However, the role of HPV infection in urological tumors is not …