British Society of Gastroenterology consensus guidelines on the management of inflammatory bowel disease in adults

CA Lamb, NA Kennedy, T Raine, PA Hendy, PJ Smith… - Gut, 2019 - gut.bmj.com
Ulcerative colitis and Crohn's disease are the principal forms of inflammatory bowel disease.
Both represent chronic inflammation of the gastrointestinal tract, which displays …

Systematic review and meta‐analysis: efficacy and safety of early biologic treatment in adult and paediatric patients with Crohn's disease

RC Ungaro, S Aggarwal, O Topaloglu… - Alimentary …, 2020 - Wiley Online Library
Background There is an increasing body of evidence showing that earlier use of biologics
improves clinical outcomes in Crohn's disease (CD). Aim To perform a systematic review …

ACG clinical guideline: management of Crohn's disease in adults

GR Lichtenstein, EV Loftus, KL Isaacs… - Official journal of the …, 2018 - journals.lww.com
Crohn's disease is an idiopathic inflammatory disorder of unknown etiology with genetic,
immunologic, and environmental influences. The incidence of Crohn's disease has steadily …

Adalimumab monotherapy and a combination with azathioprine for Crohn's disease: a prospective, randomized trial

T Matsumoto, S Motoya, K Watanabe… - Journal of Crohn's …, 2016 - academic.oup.com
Abstract Background and Aims: The efficacy of azathioprine for Crohn's disease under
adalimumab treatment remains obscure. Methods: In an open-labelled prospective study …

Management of Crohn's disease in adults

GR Lichtenstein, SB Hanauer… - Official journal of the …, 2009 - journals.lww.com
Guidelines for clinical practice are intended to suggest preferable approaches to particular
medical problems as established by interpretation and collation of scientifically valid …

Mucosal healing and bacterial composition in response to enteral nutrition vs steroid-based induction therapy—a randomised prospective clinical trial in children with …

B Pigneur, P Lepage, S Mondot… - Journal of Crohn's …, 2019 - academic.oup.com
Aims Exclusive enteral nutrition [EEN] is as efficacious as corticosteroids [CS] to induce
remission in Crohn's disease [CD], without their adverse effects. EEN seems to be more …

[HTML][HTML] A review on the use of anti-TNF in children and adolescents with inflammatory bowel disease

MA Aardoom, G Veereman, L de Ridder - International journal of …, 2019 - mdpi.com
Inflammatory bowel disease (IBD) presents with disabling symptoms and may lead to
insufficient growth and late pubertal development in cases of disease onset during …

Early mucosal healing with exclusive enteral nutrition is associated with improved outcomes in newly diagnosed children with luminal Crohn's disease

Z Grover, C Burgess, R Muir, C Reilly… - Journal of Crohn's …, 2016 - academic.oup.com
Abstract Background: Exclusive Enteral Nutrition (EEN) induction in children with luminal
Crohn's disease (CD) gives early mucosal healing (MH), but the long-term benefits of EEN …

New therapeutic strategies have changed the natural history of pediatric Crohn's disease: a two-decade population-based study

D Ley, A Leroyer, C Dupont, H Sarter, V Bertrand… - Clinical …, 2022 - Elsevier
Background & Aims We evaluated the impact of immunosuppressants (IS) and anti–tumor
necrosis factor (TNF) introduction on Crohn's disease (CD) long-term outcomes in a large …

Higher infliximab trough levels are associated with better outcome in paediatric patients with inflammatory bowel disease

K van Hoeve, E Dreesen, I Hoffman… - Journal of Crohn's …, 2018 - academic.oup.com
Background The role of therapeutic drug monitoring for infliximab [IFX] therapy in children
with inflammatory bowel disease [IBD] is poorly investigated. We determined if IFX exposure …