Mainstream health economic theory implies that an expected gain in health-related quality of
life (HRQoL) produces the same value for consumers, regardless of baseline health. Several …

The detection of biomarkers in the preclinical phase of rheumatoid arthritis (RA) and recent
therapeutic advances suggest that it may be possible to identify and treat persons at high …

Purpose This study evaluates the Alzheimer disease risk perceptions of individuals who
accurately recall their genetics-based Alzheimer disease risk assessment. Methods Two …

Effective treatments for rheumatoid arthritis (RA) are available and can lead to remission for
some patients, but most patients remain on potentially toxic and expensive medications in …

Background: Recent advances in schizophrenia genetics are shedding new light on
etiopathogenesis, but issues germane to translation of findings into clinical practice are …

Background: Myths and concerns about the extent and meaning of genetic risk in
schizophrenia may contribute to significant stigma and burden for families. Genetic …

In recent years, with both the development of next‐generation sequencing approaches and
the Supreme Court decision invalidating gene patents, declining costs have contributed to …

Neuroendocrine tumours (NETs) are a heterogenous group of tumours arising from
neuroendocrine cells in several sites around the body. They include tumours of the …

The quantitative risk of cancer among BRCA1/2 gene mutation carriers is generally well-
understood, and can be communicated clearly to potential and known mutation carriers …

With the advent of widespread genomic testing for diagnostic indications and disease risk
assessment, there is increased need to optimize genetic counseling services to support the …