[HTML][HTML] Oxidative stress in the eye and its role in the pathophysiology of ocular diseases

EW Böhm, F Buonfiglio, AM Voigt, P Bachmann, T Safi… - Redox Biology, 2023 - Elsevier
Oxidative stress occurs through an imbalance between the generation of reactive oxygen
species (ROS) and the antioxidant defense mechanisms of cells. The eye is particularly …

Diabetic keratopathy: redox signaling pathways and therapeutic prospects

F Buonfiglio, J Wasielica-Poslednik, N Pfeiffer… - Antioxidants, 2024 - mdpi.com
Diabetes mellitus, the most prevalent endocrine disorder, not only impacts the retina but also
significantly involves the ocular surface. Diabetes contributes to the development of dry eye …

Progranulin Facilitates Corneal Repair Through Dual Mechanisms of Inflammation Suppression and Regeneration Promotion

D Yan, Y Zhang, Y Huang, W Ouyang - Inflammation, 2024 - Springer
The cornea serves as a vital protective barrier for the eye; however, it is prone to injury and
damage that can disrupt corneal epithelium and nerves, triggering inflammation. Therefore …

Topical insulin in neurotrophic keratopathy after diabetic vitrectomy

TK Eleiwa, AA Khater, AM Elhusseiny - Scientific Reports, 2024 - nature.com
To assess the efficacy and safety of topical insulin (TI) for treating neurotrophic keratopathy
(NK) within one-month post-diabetic vitrectomy (DV) compared to conventional non-invasive …

The role of topical insulin in ocular surface restoration: A review

I Krolo, J Behaegel, K Termote, B de Bruyn… - Survey of …, 2024 - Elsevier
Corneal epithelial defects are one of the most common ocular disorders. Restoring corneal
integrity is crucial to reduce pain and regain function, but in cases of neurotrophic or …

Wundheilung der Kornea–Pharmakologische Therapie

T Brockmann, A Simon, C Brockmann… - Die …, 2024 - Springer
Zusammenfassung Die physiologische Wundheilung der Kornea ist ein komplexer Vorgang
und greift in eine Reihe multifaktoriell bedingter Gewebeprozesse ein. Eine regelrechte …