Importance Chronic pancreatitis (CP) is a chronic inflammatory and fibrotic disease of the
pancreas with a prevalence of 42 to 73 per 100 000 adults in the United States …

Chronic pancreatitis is defined as a pathological fibro-inflammatory syndrome of the
pancreas in individuals with genetic, environmental and/or other risk factors who develop …

IgG4-related conditions affecting the digestive tract are part of a multi-organ fibro-
inflammatory disorder termed IgG4-related disease (IgG4-RD), with autoimmune pancreatitis …

Chronic pancreatitis describes a wide spectrum of fibro-inflammatory disorders of the
exocrine pancreas that includes calcifying, obstructive, and steroid-responsive forms. Use of …

It is extensively verified that continued oxidative stress and oxidative damage may lead to
chronic inflammation, which in turn can mediate most chronic diseases including cancer …

This review aimed to analyze the scientific literature on pancreatic diseases (especially
exocrine pancreatic insufficiency). This review also describes the correlation between the …

Objective The benefits of pancreatic enzyme replacement therapy (PERT) in chronic
pancreatitis (CP) are inadequately defined. We have undertaken a systematic review and …

Background: Pancreatic exocrine insufficiency (PEI) is a common serious complication in
chronic pancreatitis (CP); however, little is known about its effect on mortality in these …

Objectives: Rare pathogenic variants in the SPINK1, PRSS1, CTRC, and CFTR genes have
been strongly associated with a risk of developing chronic pancreatitis (CP). However, their …

Chronic pancreatitis is a clinical entity that results from the progressive inflammation and
irreversible fibrosis of the pancreas resulting from the cumulative injury sustained by the …