Idiopathic nephrotic syndrome often responds to immunosuppressive treatment.
Nevertheless, this syndrome—and the drugs used to treat it—remain important causes of …

Focal segmental glomerulosclerosis (FSGS) is not a disease, rather a pattern of histological
injury occurring from a variety of causes. The exact pathogenesis has yet to be fully …

Evidence from the Oxford IgA nephropathy (IgAN) cohort supports the clinical value of
subclassifying focal segmental glomerulosclerosis lesions (S1). Using the larger Validation …

To explore whether ferroptosis is involved in focal segmental glomerulosclerosis (FSGS)
and its mechanism. The FSGS rat model was constructed by single nephrectomy combined …

Background: Genetic variants in APOL1 are a major contributor to the increased risk of
kidney disease in people of recent African ancestry. Summary: Two alleles in the APOL1 …

Collapsing glomerulopathy (CG) is most often associated with fast progression to kidney
failure with an incidence apparently higher in Brazil than in other countries. However, the …

Increasing the information depth of single kidney biopsies can improve diagnostic precision,
personalized medicine and accelerate basic kidney research. Until now, information on …

Podocytopathies are a group of proteinuric glomerular disorders driven by primary podocyte
injury that are associated with a set of lesion patterns observed on kidney biopsy, ie, minimal …

Posttransplant recurrent FSGS can have a deleterious effect on allograft. Early detection of
disease recurrence with prompt treatment is optimal for clinical remission. Plasmapheresis …

Background: The familial clustering phenomenon together with environmental influences
indicates the presence of a genetic and epigenetic predisposition to systematic lupus …