[HTML][HTML] The role of glp-1 receptor agonists in insulin resistance with concomitant obesity treatment in polycystic ovary syndrome
K Bednarz, K Kowalczyk, M Cwynar, D Czapla… - International journal of …, 2022 - mdpi.com
Insulin resistance is documented in clamp studies in 75% of women with polycystic ovary
syndrome (PCOS). Although it is not included in the diagnostic criteria of PCOS, there is a …
syndrome (PCOS). Although it is not included in the diagnostic criteria of PCOS, there is a …
[HTML][HTML] Cardiovascular effects of glucagon-like peptide 1 (GLP-1) receptor agonists
FK Saraiva, AC Sposito - Cardiovascular Diabetology, 2014 - Springer
Patients with type 2 diabetes have a several-fold increased risk of developing
cardiovascular disease when compared with nondiabetic controls. Myocardial infarction and …
cardiovascular disease when compared with nondiabetic controls. Myocardial infarction and …
[HTML][HTML] Symptomatic and disease-modifying therapy pipeline for Alzheimer's disease: Towards a personalized polypharmacology patient-centered approach
Since 1906, when Dr. Alois Alzheimer first described in a patient “a peculiar severe disease
process of the cerebral cortex”, people suffering from this pathology have been waiting for a …
process of the cerebral cortex”, people suffering from this pathology have been waiting for a …
[HTML][HTML] Histone deacetylase (HDAC) inhibition improves myocardial function and prevents cardiac remodeling in diabetic mice
Y Chen, J Du, YT Zhao, L Zhang, G Lv… - Cardiovascular …, 2015 - Springer
Background Recent evidence indicates that inhibition of histone deacetylase (HDAC)
protects the heart against myocardial injury and stimulates endogenous angiomyogenesis …
protects the heart against myocardial injury and stimulates endogenous angiomyogenesis …
[HTML][HTML] Sensory nutrition and bitterness and astringency of polyphenols
Recent studies have demonstrated that the interaction of dietary constituents with taste and
olfactory receptors and nociceptors expressed in the oral cavity, nasal cavity and …
olfactory receptors and nociceptors expressed in the oral cavity, nasal cavity and …
AMPK activation by glucagon-like peptide-1 prevents NADPH oxidase activation induced by hyperglycemia in adult cardiomyocytes
M Balteau, A Van Steenbergen… - American Journal …, 2014 - journals.physiology.org
Exposure of cardiomyocytes to high glucose concentrations (HG) stimulates reactive oxygen
species (ROS) production by NADPH oxidase (NOX2). NOX2 activation is triggered by …
species (ROS) production by NADPH oxidase (NOX2). NOX2 activation is triggered by …
GLP-1 receptor agonists and heart failure in diabetes
AJ Scheen - Diabetes & metabolism, 2017 - Elsevier
The prevalence of heart failure (HF) is increasing in patients with type 2 diabetes (T2D), and
glucose-lowering agents have distinctive effects on the risk of developing HF that requires …
glucose-lowering agents have distinctive effects on the risk of developing HF that requires …
Mechanisms involved in cardioprotection induced by physical exercise
C Penna, G Alloatti, A Crisafulli - Antioxidants & redox signaling, 2020 - liebertpub.com
Significance: Regular exercise training can reduce myocardial damage caused by acute
ischemia/reperfusion (I/R). Exercise can reproduce the phenomenon of ischemic …
ischemia/reperfusion (I/R). Exercise can reproduce the phenomenon of ischemic …
A prospective randomized controlled trial of the metabolic effects of sleeve gastrectomy with transit bipartition
FR Azevedo, S Santoro, ML Correa-Giannella… - Obesity surgery, 2018 - Springer
Purpose To compare the effects of the sleeve gastrectomy with transit bipartition (SG+ TB)
procedure with standard medical therapy (SMT) in mildly obese patients with type II diabetes …
procedure with standard medical therapy (SMT) in mildly obese patients with type II diabetes …
[HTML][HTML] Changes in liraglutide-induced body composition are related to modifications in plasma cardiac natriuretic peptides levels in obese type 2 diabetic patients
CJ Li, Q Yu, P Yu, TL Yu, QM Zhang, S Lu… - Cardiovascular …, 2014 - Springer
Background and aims Liraglutide treatment can improve glycemic control with a concomitant
weight loss, but the underlying mechanism on weight loss is not completely understood …
weight loss, but the underlying mechanism on weight loss is not completely understood …