Pathophysiology and treatment of cerebral edema in traumatic brain injury
RM Jha, PM Kochanek, JM Simard - Neuropharmacology, 2019 - Elsevier
Cerebral edema (CE) and resultant intracranial hypertension are associated with
unfavorable prognosis in traumatic brain injury (TBI). CE is a leading cause of in-hospital …
unfavorable prognosis in traumatic brain injury (TBI). CE is a leading cause of in-hospital …
Blood–spinal cord barrier in spinal cord injury: a review
LY Jin, J Li, KF Wang, WW Xia, ZQ Zhu… - Journal of …, 2021 - liebertpub.com
The blood–spinal cord barrier (BSCB), a physical barrier between the blood and spinal cord
parenchyma, prevents the toxins, blood cells, and pathogens from entering the spinal cord …
parenchyma, prevents the toxins, blood cells, and pathogens from entering the spinal cord …
Revisiting traumatic brain injury: from molecular mechanisms to therapeutic interventions
Studying the complex molecular mechanisms involved in traumatic brain injury (TBI) is
crucial for developing new therapies for TBI. Current treatments for TBI are primarily focused …
crucial for developing new therapies for TBI. Current treatments for TBI are primarily focused …
Curcumin's nanomedicine formulations for therapeutic application in neurological diseases
The brain is the body's control center, so when a disease affects it, the outcomes are
devastating. Alzheimer's and Parkinson's disease, and multiple sclerosis are brain diseases …
devastating. Alzheimer's and Parkinson's disease, and multiple sclerosis are brain diseases …
Antioxidant and anti-inflammatory potential of curcumin accelerated the cutaneous wound healing in streptozotocin-induced diabetic rats
Prolonged inflammation and increased oxidative stress impairs healing in diabetics and
application of curcumin, a well known antioxidant and anti-inflammatory agent, could be an …
application of curcumin, a well known antioxidant and anti-inflammatory agent, could be an …
Curcumin attenuates acute inflammatory injury by inhibiting the TLR4/MyD88/NF-κB signaling pathway in experimental traumatic brain injury
H Zhu, C Bian, J Yuan, W Chu, X Xiang, F Chen… - Journal of …, 2014 - Springer
Background Traumatic brain injury (TBI) initiates a neuroinflammatory cascade that
contributes to substantial neuronal damage and behavioral impairment, and Toll-like …
contributes to substantial neuronal damage and behavioral impairment, and Toll-like …
Curcumin in inflammatory diseases
Curcumin (diferuloylmethane), a yellow coloring agent extracted from turmeric is also used
as a remedy for the treatment and prevention of inflammatory diseases. Acute and chronic …
as a remedy for the treatment and prevention of inflammatory diseases. Acute and chronic …
Targeting Nrf2‐Mediated Oxidative Stress Response in Traumatic Brain Injury: Therapeutic Perspectives of Phytochemicals
AG Wu, YY Yong, YR Pan, L Zhang… - Oxidative Medicine …, 2022 - Wiley Online Library
Traumatic brain injury (TBI), known as mechanical damage to the brain, impairs the normal
function of the brain seriously. Its clinical symptoms manifest as behavioral impairment …
function of the brain seriously. Its clinical symptoms manifest as behavioral impairment …
[HTML][HTML] Reactive astrocytes as therapeutic targets for CNS disorders
ME Hamby, MV Sofroniew - Neurotherapeutics, 2010 - Elsevier
Reactive astrogliosis has long been recognized as a ubiquitous feature of CNS pathologies.
Although its roles in CNS pathology are only beginning to be defined, genetic tools are …
Although its roles in CNS pathology are only beginning to be defined, genetic tools are …
High mobility group box protein‐1 promotes cerebral edema after traumatic brain injury via activation of toll‐like receptor 4
MD Laird, JS Shields, S Sukumari‐Ramesh… - Glia, 2014 - Wiley Online Library
Traumatic brain injury (TBI) is a major cause of mortality and morbidity worldwide. Cerebral
edema, a life‐threatening medical complication, contributes to elevated intracranial pressure …
edema, a life‐threatening medical complication, contributes to elevated intracranial pressure …