The architecture of biological membranes is tightly coupled to the localization, organization,
and function of membrane proteins. The organelle-specific distribution of lipids allows for the …

The novel coronavirus, which began spreading from China Wuhan and gradually spreaded
to most countries, led to the announcement by the World Health Organization on March 11 …

The major cholesterol metabolite in brain, 24 (S)-hydroxycholesterol (24S-HC), serves as a
vehicle for cholesterol removal. Its effects on neuronal function, however, have only recently …

Cholesterol is an essential component of plasma membrane and precursor of biological
active compounds, including hydroxycholesterols (HCs). HCs regulate cellular homeostasis …

RORγt is a nuclear hormone receptor that has followed an exponential success carrier. Its
modest origins as an orphan receptor cloned from human pancreas blossomed within 15 …

Cholesterol is a vital lipid molecule for mammalian cells, regulating fluidity of biological
membranes, and serving as an essential constituent of lipid rafts. Mammalian cells acquire …

Despite encouraging progresses achieved in the management of viral diseases, efficient
strategies to counteract infections are still required. The current global challenge highlighted …

Integrins are components of cell-matrix adhesions, and function as scaffolds for various
signal transduction pathways. So far no lipid ligand for integrin has been reported. Here we …

Cholesterol is a vital lipid for cellular functions. It is necessary for membrane biogenesis, cell
proliferation, and differentiation. In addition to maintaining cell integrity and permeability …

Cholesterol is an essential molecule for life. It is a component of the cell membrane, and it is
a precursor molecule for bile acids, vitamin D and steroid hormones. Cholesterol is actively …