Immunopathobiology and therapeutic targets related to cytokines in liver diseases
Chronic liver injury with any etiology can progress to fibrosis and the end-stage diseases
cirrhosis and hepatocellular carcinoma. The progression of liver disease is controlled by a …
cirrhosis and hepatocellular carcinoma. The progression of liver disease is controlled by a …
Cytokines and chemokines in HBV infection
S Zhong, T Zhang, L Tang, Y Li - Frontiers in Molecular Biosciences, 2021 - frontiersin.org
Chronic hepatitis B virus (HBV) infection remains a leading cause of hepatic inflammation
and damage. The pathogenesis of chronic hepatitis B (CHB) infection is predominantly …
and damage. The pathogenesis of chronic hepatitis B (CHB) infection is predominantly …
The good and the bad about separation anxiety: roles of IL-22 and IL-22BP in liver pathologies
J Lücke, M Sabihi, T Zhang, LF Bauditz… - Seminars in …, 2021 - Springer
The human liver fulfills several vital tasks daily and possesses an impressive ability to self-
regenerate. However, the capacity of this self-healing process can be exhausted by a variety …
regenerate. However, the capacity of this self-healing process can be exhausted by a variety …
The role of interleukins in HBV infection: A narrative review
K Dimitriadis, S Katelani, M Pappa… - Journal of Personalized …, 2023 - mdpi.com
Hepatitis B virus (HBV) infection is a worldwide medical issue with significant morbidity and
mortality, as it is the main cause of chronic liver disease and hepatocellular carcinoma …
mortality, as it is the main cause of chronic liver disease and hepatocellular carcinoma …
A Critical Role of the IL-22–IL-22 Binding Protein Axis in Hepatocellular Carcinoma
AD Giannou, J Lücke, D Kleinschmidt, AM Shiri… - Cancers, 2022 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) still poses a major challenge for curative
treatment. Although some new therapeutic options arose during the last decade, the overall …
treatment. Although some new therapeutic options arose during the last decade, the overall …
Th22/IL-22 mediates the progression of HBV-related hepatocellular carcinoma via STAT3
J Zhang, Z Liu, L Liu, M Huang, Y Huang - Cytotechnology, 2022 - Springer
T helper cell 22 are abundant in Hepatitis B Virus-related hepatocellular carcinoma tissue,
and the main cytokine interleukin 22 produced by Th22 cells is closely related to the …
and the main cytokine interleukin 22 produced by Th22 cells is closely related to the …
[HTML][HTML] IL-22 in Atopic Dermatitis
Atopic dermatitis (AD) is a prevalent and chronic inflammatory skin condition characterized
by a multifaceted pathophysiology that gives rise to diverse clinical manifestations. The …
by a multifaceted pathophysiology that gives rise to diverse clinical manifestations. The …
IL-22 signaling promotes sorafenib resistance in hepatocellular carcinoma via STAT3/CD155 signaling axis
J Chen, S Sun, H Li, X Cai, C Wan - Frontiers in Immunology, 2024 - frontiersin.org
Introduction Sorafenib is currently the first-line treatment for patients with advanced
hepatocellular carcinoma (HCC). Nevertheless, sorafenib resistance remains a huge …
hepatocellular carcinoma (HCC). Nevertheless, sorafenib resistance remains a huge …
IL-22 promotes liver regeneration after portal vein ligation
T Zhang, P Seeger, Y Simsek, M Sabihi, J Lücke… - Heliyon, 2024 - cell.com
Background Insufficient remnant liver volume (RLV) after the resection of hepatic
malignancy could lead to liver failure and mortality. Portal vein ligation (PVL) prior to …
malignancy could lead to liver failure and mortality. Portal vein ligation (PVL) prior to …
The role of IL-22 in cancer
ZE Hunzeker, L Zhao, AM Kim, JM Parker, Z Zhu… - Medical Oncology, 2024 - Springer
Interleukin-22, discovered in the year of 2000, is a pleiotropic Th17 cytokine from the IL-10
family of cytokines. IL-22 signals through the type 2 cytokine receptor complex IL-22R and …
family of cytokines. IL-22 signals through the type 2 cytokine receptor complex IL-22R and …