[HTML][HTML] Optical biosensors for therapeutic drug monitoring

V Garzón, DG Pinacho, RH Bustos, G Garzón… - Biosensors, 2019 - mdpi.com
Therapeutic drug monitoring (TDM) is a fundamental tool when administering drugs that
have a limited dosage or high toxicity, which could endanger the lives of patients. To carry …

Lateral flow assays for food analyses: Food contaminants, allergens, toxins, and beyond

B İnce, İ Uludağ, B Demirbakan, C Özyurt… - TrAC Trends in …, 2023 - Elsevier
Food safety is a major issue because of the prevalence of pathogens, chemicals, and other
potentially harmful substances in food products. Because of this, the creation of a reliable …

Carbon quantum dots prepared by pyrolysis: investigation of the luminescence mechanism and application as fluorescent probes

C Wang, M Yang, H Shi, Z Yao, E Liu, X Hu, P Guo… - Dyes and …, 2022 - Elsevier
In this work, the effect of reaction conditions on the preparation of CQDs by pyrolysis was
studied. More specifically, CQDs-1 with single emission peak of blue fluorescence and …

[HTML][HTML] Update on therapeutic drug monitoring of beta-lactam antibiotics in critically ill patients—a narrative review

J Stašek, F Keller, V Kočí, J Klučka, E Klabusayová… - Antibiotics, 2023 - mdpi.com
Beta-lactam antibiotics remain one of the most preferred groups of antibiotics in critical care
due to their excellent safety profiles and their activity against a wide spectrum of pathogens …

A review of bioanalytical methods for the therapeutic drug monitoring of β-lactam antibiotics in critically ill patients: Evaluation of the approaches used to develop and …

YS Caro, MS Cámara, MM De Zan - Talanta, 2020 - Elsevier
Due to their broad spectrum of activity and wide therapeutic index, β-lactam antibiotics (β-
LA) are commonly used to treat severe sepsis in critically ill patients in intensive care units …

Ultrasensitive immunochromatographic strip for fast screening of piperacillin in milk based on a monoclonal antibody

Y Chen, S Song, L Xu, H Kuang, C Xu, L Guo - Journal of Food …, 2023 - Elsevier
We developed a lateral flow immunoassay (LFIA) based on a sensitive and specific
monoclonal antibody against piperacillin (PIP) with a half-maximal inhibitory concentration …

Therapeutic drug monitoring of antibiotic drugs: the role of the clinical laboratory

M Shipkova, H Jamoussi - Therapeutic Drug Monitoring, 2022 - journals.lww.com
Background: Therapeutic drug monitoring (TDM) of anti-infective drugs is an increasingly
complex field, given that in addition to the patient and drug as 2 usual determinants, its …

Simultaneous determination of six antibiotics in human serum by high‐performance liquid chromatography with UV detection

T Roth, L Weber, M Niestroj, F Cipa… - Biomedical …, 2021 - Wiley Online Library
Antibiotics are widely used in intensive care patients to treat severe infections. To avoid
bacterial resistance or toxic side effects, the determination of serum concentration of ABs is …

Rapid detection of 21 β-lactams using an immunochromatographic assay based on the mutant BlaR-CTD protein from Bacillus licheniformis

Y Li, X Xu, L Liu, H Kuang, L Xu, C Xu - Analyst, 2020 - pubs.rsc.org
In this study, a gold immunochromatographic assay (GICA) based on a penicillin receptor
protein (PBP) is proposed to simultaneously detect penicillin, cephalosporin, and …

Time-resolved fluorescence microspheres-antibody-penicillin-binding protein assisted construction of immunochromatographic assay for sensitive detection of 22 β …

Y Sun, X Deng, C Luo, W Ma, W Liu, J Wang, Q Li… - Microchimica Acta, 2024 - Springer
A sensitive immunochromatographic assay (ICA) using time-resolved fluorescence
microspheres (TRFMs) coupled with an indirect-labeling mode was developed for …