Emerging topics in dementia care and services

JL Wolff, JF Benge, CK Cassel… - Journal of the …, 2021 - Wiley Online Library
Abstract Background The National Institute on Aging (NIA), in conjunction with the
Department of Health and Human Services as part of the National Alzheimer's Project Act …

The major hypotheses of Alzheimer's disease: related nanotechnology-based approaches for its diagnosis and treatment

C Cáceres, B Heusser, A Garnham, E Moczko - Cells, 2023 - mdpi.com
Alzheimer's disease (AD) is a well-known chronic neurodegenerative disorder that leads to
the progressive death of brain cells, resulting in memory loss and the loss of other critical …

Effect of reduction in brain amyloid levels on change in cognitive and functional decline in randomized clinical trials: an instrumental variable meta‐analysis

M Pang, L Zhu, A Gabelle, AR Gafson… - Alzheimer's & …, 2023 - Wiley Online Library
Introduction Whether the reduction in brain amyloid beta (Aβ) plaque alone may
substantially slow cognitive and functional decline in patients with dementia or mild …

[PDF][PDF] Brain PET imaging: frontotemporal dementia

J Ward, M Ly, CA Raji - PET clinics, 2023 - Elsevier
Brain PET is crucial in the diagnosis of neurodegenerative disorders, especially
frontotemporal dementia (FTD) due to its complex presentation and constellation of …

Diagnostic performance of automated plasma amyloid-β assays combined with pre-analytical immunoprecipitation

HW Klafki, J Vogelgsang, E Manuilova, C Bauer… - Alzheimer's research & …, 2022 - Springer
Background Measurements of the amyloid-β (Aβ) 42/40 ratio in blood plasma may support
the early diagnosis of Alzheimer's disease and aid in the selection of suitable participants in …

Plasma p‐tau181/Aβ1‐42 ratio predicts Aβ‐PET status and correlates with CSF‐p‐tau181/Aβ1‐42 and future cognitive decline

CJ Fowler, E Stoops, SR Rainey‐Smith… - Alzheimer's & …, 2022 - Wiley Online Library
Abstract Background In Alzheimer's disease (AD), plasma amyloid beta (Aβ) 1‐42 and
phosphorylated tau (p‐tau) predict high amyloid status from Aβ positron emission …

Acceptable performance of blood biomarker tests of amyloid pathology—recommendations from the Global CEO Initiative on Alzheimer's Disease

SE Schindler, D Galasko, AC Pereira… - Nature Reviews …, 2024 - nature.com
Anti-amyloid treatments for early symptomatic Alzheimer disease have recently become
clinically available in some countries, which has greatly increased the need for biomarker …

The structural combination of SIL and MODAG scaffolds fails to enhance binding to α-synuclein but reveals promising affinity to amyloid β

A Di Nanni, RS Saw, GD Bowden, NSR Bidesi… - Molecules, 2023 - mdpi.com
A technique to image α-synuclein (αSYN) fibrils in vivo is an unmet scientific and clinical
need that would represent a transformative tool in the understanding, diagnosis, and …

Improvement of electroacupuncture on APP/PS1 transgenic mice in behavioral probably due to reducing deposition of Aβ in hippocampus

RQ Sun, ZD Wang, J Zhao, S Wang… - The Anatomical …, 2021 - Wiley Online Library
Alzheimer's disease (AD) is a fatal neurodegenerative disease for which currently no cure is
available. Electroacupuncture (EA) has been widely used in China as an alternative …

Current status of PET tracers for the early diagnosis of Alzheimer's disease

Y Li, T Liu, Q Zeng, M Cui - TrAC Trends in Analytical Chemistry, 2024 - Elsevier
Positron emission tomography (PET) is a non-invasive imaging technology that can reveal
molecular alterations in the brains of Alzheimer's disease (AD) patients with high sensitivity …